Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [3]
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Validation data
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- Product number
- NB200-312 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB200-312, RRID:AB_10001251
- Product name
- Mouse Monoclonal JAB1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. This is specific for JAB-1.
- Reactivity
- Human, Mouse, Drosophila
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1.
The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis.
Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif.
The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.
The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.
Mitsuhashi T, Yonemoto J, Sone H, Kosuge Y, Kosaki K, Takahashi T
Proceedings of the National Academy of Sciences of the United States of America 2010 Sep 14;107(37):16331-5
Proceedings of the National Academy of Sciences of the United States of America 2010 Sep 14;107(37):16331-5
The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis.
da Silva Correia J, Miranda Y, Leonard N, Ulevitch RJ
The Journal of biological chemistry 2007 Apr 27;282(17):12557-65
The Journal of biological chemistry 2007 Apr 27;282(17):12557-65
Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif.
Burger-Kentischer A, Finkelmeier D, Thiele M, Schmucker J, Geiger G, Tovar GE, Bernhagen J
FEBS letters 2005 Mar 14;579(7):1693-701
FEBS letters 2005 Mar 14;579(7):1693-701
The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.
Doronkin S, Djagaeva I, Beckendorf SK
Developmental cell 2003 May;4(5):699-710
Developmental cell 2003 May;4(5):699-710
The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.
Doronkin S, Djagaeva I, Beckendorf SK
Developmental cell 2003 May;4(5):699-710
Developmental cell 2003 May;4(5):699-710
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: JAB1 Antibody (8H8.5) [NB200-312] - HeLa whole cell lysate
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: JAB1 Antibody (8H8.5) [NB200-312] - D10 T cells were lysed in IP buffer (20mM Tris-HCl, pH 7. 5, 50mM NaCl, 50mM NaF, 10mM -glycerophosphate, 1% Triton X-100, 1mM PMSF).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: JAB1 Antibody (8H8.5) [NB200-312]