Antibody data
- Antibody Data
- Antigen structure
- References [179]
- Comments [0]
- Validations [0]
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- Product number
- 27675-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- MUC2 antibody
- Antibody type
- Polyclonal
- Description
- MUC2 antibody (Cat. #27675-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, Mouse and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Prim-O-glucosylcimifugin ameliorates DSS-induced ulcerative colitis via suppressing NLRP3 inflammasome activation.
JianPi QingRe HuoXue Formula targets Cadherin-17 to induce apoptosis in chronic atrophic gastritis with intestinal metaplasia.
Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol-Induced Intestinal Injury via Microbiota-Dependent and -Independent AHR Activation.
Dietary N-acetylneuraminic acid maintains intestinal homeostasis and protects against aging- and inflammation-associated colonic dysfunction.
Probiotic-derived extracellular vesicles attenuate cholestatic liver damage via gut-liver axis.
Weiyan Tongluo Granules attenuate gastric intestinal metaplasia through PPARγ/NF-κB/CDX2 signaling pathway.
EGCG Derivatives Alleviate Diquat-Induced Liver and Gut Damage in Mice by Activating an Antioxidant Pathway and Enhancing Barrier Function.
Targeting NAT10 alleviates colonic senescence and elderly-onset colitis by disrupting N4-acetylation of DYRK1A.
Functional characteristics of a pig 2D intestinal organoid model as an in vitro platform for nutritional studies.
A Feline Milk-Drived Pediococcus acidilactici M22 Alleviates Escherichia coli O157:H7 Infection Through Anti-Adhesion, Anti-Inflammation, and Microbiota Modulation.
Lactiplantibacillus plantarum LPPerfectus001 Alleviating Irritable Bowel Syndrome in Mice by Modulating Gut Microbiota and NF-κB Signaling Pathway.
Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review.
Microbiota-derived IPA protects against colitis by regulating intestinal HMGCS2-mediated ketogenesis to facilitate mucosal healing.
A microbiota-IPA axis facilitates intestinal stem cell-mediated regeneration in colitis through a Hopx-associated program.
Gut microbiota-derived trimethylamine N-oxide contributes to cardiomyocyte pyroptosis and cardiac injury via the tRF-Glu-ANT1-GSDMD axis.
Adenosine from high-fat-diet-tolerant monkey-derived Limsolactobacillus reuteri MacFasB02 modulates cholesterol metabolism to alleviate hyperlipidemia and inflammation.
Methanobrevibacter smithii activates immune microenvironment of intestinum tenue in a mouse model.
Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a (-/-) mice.
A 4-guanidinobutanoic acid-SLC36A1 axis drives a microbiota‒host feedback loop to regulate intestinal homeostasis.
Xanthoxylin alleviates dextran sulfate sodium (DSS)-induced colitis by targeting macrophage infiltration via the tumor necrosis factor (TNF) /nuclear factor-kappa B (NF-κB) signaling pathway.
Dihydroartemisinin facilitates intestinal mucosal healing in inflammatory bowel disease by targeting 11βHSD-1 to reprogram macrophage metabolism.
Sex-Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu-erh Tea.
Effects and mechanisms of nobiletin on gut motility by coordinating bile acid signaling via dual ileal-colonic axes in STC model mice.
Polydisperse polystyrene microplastics exacerbate colitis through gut microbiota-butyrate-PPARγ axis disruption in mice.
Atlas of innate immune responses to experimental cholera and IL22 treatment demonstrates protection by mucus-secreting cells.
Luteolin improves precancerous conditions of the gastric mucosa by binding STAT3 and inhibiting LCN2 expression.
FMO5 Plays a Sex-specific Role in Goblet Cell Maturation and Mucus Barrier Formation.
Gegen Qinlian Decoction Ameliorated DSS-Induced Colitis by Attenuating Inflammation, Restoring Intestinal Mucosal Barrier and Modulating Gut Microbiota.
Wuda Granule Alleviates DSS-Induced Colitis in Mice by Inhibiting Inflammation, Protecting Intestinal Barrier and Reducing Oxidative Stress Through Nrf2/Keap1/HO-1 Pathway.
Dahuang gancao dandelion decoction regulates intestinal flora and inhibits NF-κB/ARA signaling pathway to alleviate ulcerative colitis.
Lily polysaccharides alleviate colitis through the microbiota-N8-acetylspermidine-cGAS-STING signaling axis.
Lyophyllum decastes-derived polysaccharides alleviate DSS-induced colitis in mice by suppressing inflammation, enhancing intestinal barrier integrity, and restoring gut microbiota homeostasis.
Proteus mirabilis exacerbates ulcerative colitis by inhibiting mucin production.
Preclinical evaluation of 6-Gingerol in modulating gut microbiota and SCFAs to mitigate Clostridium difficile-associated diarrhea in mice.
Vespa orientalis pupae peptide hydrolysates modulate NF-κB signaling in LTA-induced pneumonia from clinical Enterococcus faecalis isolates: implications for gut microbiota.
Ovotransferrin ameliorated intestinal barrier dysfunction in DSS-induced ulcerative colitis mice via inhibition of PI3K-Akt/MAPK signaling pathways and modulation of tissue metabolism.
Metal-Organic Framework-Remodeled Gut Microbiota Alleviates Colonic Inflammation via Selective Modulation of Roseburia intestinalis.
Structural Variations in Ulcerative Colitis-associated Escherichia coli Reduce Fructose Utilization and Aggravate Inflammation Under High-Fructose Diet.
Lychee Fermented by Mixed Probiotic Strains Alleviates D-Galactose-Induced Skeletal Muscle and Intestinal Aging in Mice.
Enhancement of Intestinal Barrier Function by Butyryl-Fructooligosaccharides via Microbiota-Host Interactions in Colonic Organoid Models.
Nuclear receptor Nr1d1 links sleep deprivation to intestinal homeostasis via microbiota-derived taurine.
Resveratrol attenuates Citrobacter rodentium-infected colitis by remodeling the gut microbiota structure and inhibiting CD4(+) cell activation in mice.
ALKBH8-mediated codon-specific translation promotes colorectal tumorigenesis.
Silymarin ameliorates diet-induced gallstone formation by regulating gut microbiota-derived GCDCA to suppress ferroptosis-ROS-NFκB signaling pathway.
Lactiplantibacillus plantarum BD7807 ameliorates high-fat diet-induced lipid metabolic disorders and intestinal dysfunction via SCFAs-GPR43 pathway.
Yuzhi Zhixue Granules regulate the JAK/STAT pathway to affect T-cell differentiation in the colon of ulcerative colitis.
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Chronic psychological stress-orchestrated glial-ILC3 circuit exacerbates intestinal inflammation and depression.
Novel Role of Gut-Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure.
Functional and morphological characterisation of human colonoid-derived monolayers under inflammatory conditions.
Effects of Abrus cantoniensis capsule on gut microbiota and intestinal barrier in mice infected with alveolar echinococcosis.
Autism-Associated Gut Microbiota-Derived Enterococcus facium Modulates Gut-Brain Axis Function and Behavior in Mice.
Berberine ameliorates high-fat diet-induced metabolic disorders through promoting gut Akkermansia and modulating bile acid metabolism.
Antibacterial hyaluronic acid hydrogel with sustained release of larazotide as effective colitis treatment.
Proline rich-39 (PR-39) antimicrobial protein alleviated lipopolysaccharide-induced intestinal barrier dysfunction in piglets by altering intestinal flora associated bile acid metabolism and in turn regulating TGR-5/NF-κB/MLCK/MLC pathway.
β-1,3-glucans from Euglena Gracilis protects against ulcerative colitis via modulating the gut barrier, T-cell immunity and gut microbiota.
ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity.
Evaluation of Indigo Naturalis Prepared Using a Novel Method: Therapeutic Effects on Experimental Ulcerative Colitis in Mice.
Polygonatum cyrtonema Hua polysaccharide alleviates ulcerative colitis via gut microbiota-independent modulation of inflammatory immune response.
Huangqin decoction alleviated irinotecan-induced diarrhea by inhibiting endoplasmic reticulum stress through activating AMPK/mTOR-mediated autophagy.
A novel scheme for non-invasive drug delivery with a magnetically controlled drug delivering capsule endoscope.
Runchangningshen paste activates NLRP6 inflammasome-mediated autophagy to stimulate colonic mucin-2 secretion and modulates mucosal microbiota in functional constipation.
Multi-omics approaches reveal the therapeutic mechanism of Naoxintong capsule against ischemic stroke.
Bifidobacterium longum BL300 alleviates DSS-induced Colitis by promoting IgA-mediated Gut Microbiota homeostasis.
Dual Role of NRF2 in Pancreatic Precursor Lesions.
Music intervention mitigates LPS-induced gut barrier disruption and immune stress in broilers via TLR4/NF-κB regulation.
Engineered tumor microspheres via microfluidics and decellularized extracellular matrix for high-throughput organoid-based drug screening.
Acid-Enzyme Derived Agarotriose Facilitates Anti-Inflammatory Activity for Dextran Sulfate Sodium-Induced Colitis Alleviation as a Food Supplement.
Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice.
Agrocybe cylindracea Polysaccharides Ameliorate DSS-Induced Colitis by Restoring Intestinal Barrier Function and Reprogramming Immune Homeostasis via the Gut-Liver Axis.
Multi-Omics Integration Reveals Gut Microbiota-Bile Acid Crosstalk Underlying Baizhu Shaoyao Decoction's Therapeutic Efficacy in Weaning Stress of Piglets.
Cimicifuga heracleifolia kom. Attenuates ulcerative colitis through the PI3K/AKT/NF-κB signaling pathway.
Gut bacterial L-lysine alters metabolism and histone methylation to drive dendritic cell tolerance.
Lentinan's effect on gut microbiota and inflammatory cytokines in 5-FU-induced mucositis mice.
Targeting Catenibacterium mitsuokai with icariin modulates gut microbiota and improves hepatic lipid metabolism in intrauterine growth restriction.
Photo-Crosslinking Hydrogel Based on Porcine Small Intestinal Submucosa Decellularized Matrix/Fish Collagen/GelMA for Culturing Small Intestinal Organoids and Repairing Intestinal Defects.
Neohesperidin Mitigates High-Fat-Diet-Induced Colitis In Vivo by Modulating Gut Microbiota and Enhancing SCFAs Synthesis.
LGR4 promotes proliferation and homing via activation of the NF‑κB signaling pathway in multiple myeloma.
Organoid-based in vitro system and reporter for the study of Cryptosporidium parvum sexual reproduction.
Ligustilide improves functional constipation by non-covalently activating TRPA1 in colon tissue.
Terpine-4-ol alleviates lipopolysaccharide-induced intestinal injury in weaned piglets by regulating intestinal epithelial cell homeostasis via the Wnt/β-catenin signaling pathway.
Novel role of FTO in regulation of gut-brain communication via Desulfovibrio fairfieldensis-produced hydrogen sulfide under arsenic exposure.
Dietary iron attenuates Clostridioides difficile infection via modulation of intestinal immune response and gut microbiota.
The Therapeutic Effect and Mechanism of Lactobacillus gardneri on Nonalcoholic Fatty Liver Disease.
Revealing the Immune and Inflammatory Mechanisms of Electroacupuncture in Male IBS Rats Through Multi-Omics Analysis.
Integrative analysis of gut microbiome and serum metabolomics explores the therapeutic mechanism of tongfeng qingxiao prescription in treating gouty arthritis.
Six Weeks of Moderate-Intensity Treadmill Exercise Improves Intestinal Barrier and Intestinal Inflammation in Parkinson's Disease Mice.
Gut microbiota promote the propagation of pathologic α-syn from gut to brain in a gut-originated mouse model of Parkinson's disease.
Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409-Ube2k-Foxp3 Axis in Regulatory T Cells.
Banxia Xiexin Decoction inhibits colitis-associated colorectal cancer development by modulating STAT3 signaling and gut microbiota.
Gut microbiota contributes to protection against porcine deltacoronavirus infection in piglets by modulating intestinal barrier and microbiome.
Gut microbiota-derived UDCA enhanced by metformin inhibits FXR to activate autophagy against MCD diet-induced NAFLD in mice.
Colon-Targeted Mucoadhesive PLGA Microspheres Loaded with Ramulus Mori Alkaloids for Enhanced Water-Soluble Drug Delivery in Ulcerative Colitis Treatment.
Green Tea Ameliorates Depression-Like Behavior and Cognitive Impairment Induced by High-Fat Diet and Chronic Mild Stress.
Polysaccharides derived from golden mushroom (Cantharellus cibarius Fr.) modulate gut microbiota and enhance intestinal barrier function to ameliorate dextran sulfate sodium-induced colitis in mice.
Modified Gegen Qinlian Decoction modulated the gut microbiome and bile acid metabolism and restored the function of goblet cells in a mouse model of ulcerative colitis.
Btbd8 deficiency reduces susceptibility to colitis by enhancing intestinal barrier function and suppressing inflammation.
Fmo5 plays a sex-specific role in goblet cell maturation and mucus barrier formation.
Procyanidin B1 and p-coumaric acid from whole highland barley ameliorated HFD-induced impaired glucose tolerance via small intestinal barrier and hepatic glucose metabolism.
Bitter-tasting drugs tune GDF15 and GLP-1 expression via bitter taste or motilin receptors in the intestine of patients with obesity.
Protective properties of Ophiopogonin D in DSS-induced colitis: insights into microbiota modulation.
Combined effects of TiO(2) nanoparticle and fipronil co-exposure on microbiota in mouse intestine.
ADORA3 activation promotes goblet cell differentiation via enhancing HMGCS2-mediated ketogenesis in ulcerative colitis.
CTPAD: an interactive web application for comprehensive transcriptomic profiling in allergic diseases.
Dietary nitrate maintains intestinal epithelia homeostasis in aged mice.
Microbiota-derived succinic acid mediates attenuating effect of dietary tomato juice supplementation on steatohepatitis through enhancing intestinal barrier.
Alginate Oligosaccharides Enhance Gut Microbiota and Intestinal Barrier Function, Alleviating Host Damage Induced by Deoxynivalenol in Mice.
Lycium barbarum polysaccharide remodels colon inflammatory microenvironment and improves gut health.
POFUT1 and PLAGL2 are characteristic markers of mucinous colorectal cancer associated with MUC2 expression.
Social isolation induces intestinal barrier disorder and imbalances gut microbiota in mice.
Prevotella histicola ameliorates DSS-induced colitis by inhibiting IRE1α-JNK pathway of ER stress and NF-κB signaling.
Bound Polyphenols of Oat Bran Released by Gut Microbiota Mitigate High Fat Diet-Induced Oxidative Stress and Strengthen the Gut Barrier via the Colonic ROS/Akt/Nrf2 Pathway.
PIM1-HDAC2 axis modulates intestinal homeostasis through epigenetic modification.
Impact of hepatocyte growth factor on the colonic morphology and gut microbiome in short bowel syndrome rat model.
Leveraging Temporal Wnt Signal for Efficient Differentiation of Intestinal Stem Cells in an Organoid Model.
Infant feces-derived Lactobacillus gasseri FWJL-4 mitigates experimental necrotizing enterocolitis via acetate production.
The protective effect of Schisandra chinensis (Turcz.) Baill. polysaccharide on DSS-induced ulcerative colitis in mice via the modulation of gut microbiota and inhibition of NF-κB activation.
Multi-omics reveals the protective effects of curcumin against AFB1-induced oxidative stress and inflammatory damage in duckling intestines.
peu-MIR2916-p3-enriched garlic exosomes ameliorate murine colitis by reshaping gut microbiota, especially by boosting the anti-colitic Bacteroides thetaiotaomicron.
Fucoidan alleviated dextran sulfate sodium-induced ulcerative colitis with improved intestinal barrier, reshaped gut microbiota composition, and promoted autophagy in male C57BL/6 mice.
Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway.
Gut-Microbiota-Derived Butyric Acid Overload Contributes to Ileal Mucosal Barrier Damage in Late Phase of Chronic Unpredictable Mild Stress Mice.
Terpinen-4-ol Improves the Intestinal Barrier Function of the Colon in Immune-Stressed Weaning Piglets.
Berberine ameliorates dextran sulfate sodium -induced colitis through tuft cells and bitter taste signalling.
Gut-derived memory γδ T17 cells exacerbate sepsis-induced acute lung injury in mice.
1,25-Dihydroxyvitamin D Enhances the Regenerative Function of Lgr5(+) Intestinal Stem Cells In Vitro and In Vivo.
Faecalibacterium prausnitzii Supplementation Prevents Intestinal Barrier Injury and Gut Microflora Dysbiosis Induced by Sleep Deprivation.
A commensal protozoan attenuates Clostridioides difficile pathogenesis in mice via arginine-ornithine metabolism and host intestinal immune response.
Ellagic acid alleviates TNBS-induced intestinal barrier dysfunction by regulating mucin secretion and maintaining tight junction integrity in rats.
Lactiplantibacillus plantarum L47 and inulin alleviate enterotoxigenic Escherichia coli induced ileal inflammation in piglets by upregulating the levels of α-linolenic acid and 12,13-epoxyoctadecenoic acid.
Live and pasteurized Akkermansia muciniphila decrease susceptibility to Salmonella Typhimurium infection in mice.
Organoids transplantation attenuates intestinal ischemia/reperfusion injury in mice through L-Malic acid-mediated M2 macrophage polarization.
The metabolite butyrate produced by gut microbiota inhibits cachexia-associated skeletal muscle atrophy by regulating intestinal barrier function and macrophage polarization.
Bile Acid Derivatives Effectively Prevented High-Fat Diet-Induced Colonic Barrier Dysfunction.
A possible but unrecognized risk of acceptable daily intake dose triazole pesticides exposure-bile acid disturbance induced pharmacokinetic changes of oral medication.
The protective effects of electroacupuncture on intestinal barrier lesions in IBS and UC model.
Shaoyao decoction restores the mucus layer in mice with DSS-induced colitis by regulating Notch signaling pathway.
A high-sucrose diet causes microbiota composition shift and promotes the susceptibility of mice to Salmonella Typhimurium infection.
Single-cell transcriptomics reveals intestinal cell heterogeneity and identifies Ep300 as a potential therapeutic target in mice with acute liver failure.
Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis.
Budget-Friendly Generation, Biochemical Analyses, and Lentiviral Transduction of Patient-Derived Colon Organoids.
Impact of structurally diverse polysaccharides on colonic mucin O-glycosylation and gut microbiota.
Succinate signaling attenuates high-fat diet-induced metabolic disturbance and intestinal barrier dysfunction.
Microbiota-derived tryptophan metabolites indole-3-lactic acid is associated with intestinal ischemia/reperfusion injury via positive regulation of YAP and Nrf2.
Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.
Qingchang Wenzhong Decoction Prevents the Occurrence of Intestinal Tumors by Regulating Intestinal Microbiota and Gasdermin E.
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
RhoB affects colitis through modulating cell signaling and intestinal microbiome.
Calpain-1: a Novel Antiviral Host Factor Identified in Porcine Small Intestinal Mucus.
Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice.
Efficacy of Probiotic Consortium Transplantation on Experimental Necrotizing Enterocolitis.
Enhanced therapeutic effect on colitis with powder formulations of Painong San associated with the promotion of intestinal adhesion and absorption.
Effective Oral RNA Interference (RNAi) Administration to Adult Anopheles gambiae Mosquitoes.
Protein restriction during the fetal period upregulates IL1B and IL13 while suppressing Muc2 expression in the jejunum of mice after weaning.
The Protective Effects of Apigenin Against Radiation-Induced Intestinal Injury.
Chitosan Oligosaccharide Attenuates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction through Suppressing the Inflammatory Response and Oxidative Stress in Mice.
Microbial hydrogen economy alleviates colitis by reprogramming colonocyte metabolism and reinforcing intestinal barrier.
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
Dietary κ-carrageenan facilitates gut microbiota-mediated intestinal inflammation.
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.
Diarrhoeal pathogenesis in Salmonella infection may result from an imbalance in intestinal epithelial differentiation through reduced Notch signalling.
Anemone chinensis Bunge aqueous enema alleviates dextran sulfate sodium-induced colitis via inhibition of inflammation and regulation of the colonic mucosal microbiota.
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Polydatin has anti-inflammatory and antioxidant effects in LPS-induced macrophages and improves DSS-induced mice colitis.
Arsenic exposure induces intestinal barrier damage and consequent activation of gut-liver axis leading to inflammation and pyroptosis of liver in ducks.
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Shaoyao decoction attenuates DSS-induced ulcerative colitis, macrophage and NLRP3 inflammasome activation through the MKP1/NF-κB pathway.
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
Clostridium tyrobutyricum Protects against LPS-Induced Colonic Inflammation via IL-22 Signaling in Mice.
λ-carrageenan exacerbates Citrobacter rodentium-induced infectious colitis in mice by targeting gut microbiota and intestinal barrier integrity.
Alhagi honey polysaccharides attenuate intestinal injury and immune suppression in cyclophosphamide-induced mice.
Diverse cellular morphologies during lumen maturation in Anopheles gambiae larval salivary glands.
Teasaponin Ameliorates Murine Colitis by Regulating Gut Microbiota and Suppressing the Immune System Response.
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
Interleukin-10 expands transit-amplifying cells while depleting Lgr5(+) stem cells via inhibition of Wnt and notch signaling.
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
SRC-3 protects intestine from DSS-induced colitis by inhibiting inflammation and promoting goblet cell differentiation through enhancement of KLF4 expression.
Wang F, Xiong X, Ruan Q, Zhang D, Huang C, Xie T, Cheng L
Frontiers in pharmacology 2026;17:1750305
Frontiers in pharmacology 2026;17:1750305
JianPi QingRe HuoXue Formula targets Cadherin-17 to induce apoptosis in chronic atrophic gastritis with intestinal metaplasia.
Mai Z, Zheng Y, Xie J, Wen Y, Wang S, Huang Y, Tan H, Chen J, Wang C, Tao Y, Chen Q, Liu F, Liang Y, Chen X, Zhao Y, Li P, Yang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158037
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158037
Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol-Induced Intestinal Injury via Microbiota-Dependent and -Independent AHR Activation.
Cui C, Zhang B, Tang J, Hou J, Qiu Y, Gao K, Wang L, Jiang Z, Yang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e22912
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e22912
Dietary N-acetylneuraminic acid maintains intestinal homeostasis and protects against aging- and inflammation-associated colonic dysfunction.
Li XX, Shi JN, Guan Z, Zeng SY, Luo Y, Gong XX, He SY, Xu KX, Yang Y, Yin H, Wang ZX, Xie H, Shi LJ
International immunopharmacology 2026 May 15;177:116531
International immunopharmacology 2026 May 15;177:116531
Probiotic-derived extracellular vesicles attenuate cholestatic liver damage via gut-liver axis.
Liu X, Wang Y, Medina AA, Liu D, Liu J, Tang W, Wang M, Chen X, Huang K, Liu M, Wang C, Liu Y
Pharmacological research 2026 Mar;225:108152
Pharmacological research 2026 Mar;225:108152
Weiyan Tongluo Granules attenuate gastric intestinal metaplasia through PPARγ/NF-κB/CDX2 signaling pathway.
Liang Y, Su S, Jin T, Mou J, Wu H, Yan N, Li X, Yao S, Wen Y, Liu F, Li P
Chinese medicine 2026 Mar 4;21(1)
Chinese medicine 2026 Mar 4;21(1)
EGCG Derivatives Alleviate Diquat-Induced Liver and Gut Damage in Mice by Activating an Antioxidant Pathway and Enhancing Barrier Function.
Xu L, Luo C, Gao X, Yuan J, Fu B
Animals : an open access journal from MDPI 2026 Mar 19;16(6)
Animals : an open access journal from MDPI 2026 Mar 19;16(6)
Targeting NAT10 alleviates colonic senescence and elderly-onset colitis by disrupting N4-acetylation of DYRK1A.
Chen J, Xue M, Mi S, Fu A, Chen W, Sun Y, Xia S, Ge Q, Luo J, Yu Q, Wang L, Chen S
Nature communications 2026 Mar 1;17(1)
Nature communications 2026 Mar 1;17(1)
Functional characteristics of a pig 2D intestinal organoid model as an in vitro platform for nutritional studies.
Joo SS, Gu BH, Lee E, Oh E, Kim M, Jung H, Kim M
Journal of animal science and technology 2026 Jan;68(1):236-257
Journal of animal science and technology 2026 Jan;68(1):236-257
A Feline Milk-Drived Pediococcus acidilactici M22 Alleviates Escherichia coli O157:H7 Infection Through Anti-Adhesion, Anti-Inflammation, and Microbiota Modulation.
Gong X, Wang X, Huang H, Han J, Wang Z, Wen M
Microorganisms 2026 Jan 30;14(2)
Microorganisms 2026 Jan 30;14(2)
Lactiplantibacillus plantarum LPPerfectus001 Alleviating Irritable Bowel Syndrome in Mice by Modulating Gut Microbiota and NF-κB Signaling Pathway.
Wang Y, Bai X, Jing Y, Feng X, Guo Y, Hao Y, Su D, Zhai Z
Foods (Basel, Switzerland) 2026 Jan 23;15(3)
Foods (Basel, Switzerland) 2026 Jan 23;15(3)
Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review.
Wang C, Liu Y, Liu Y, Li B, Hou X, Lu B, Chen Z, Ning S
Experimental and therapeutic medicine 2026 Feb;31(2):48
Experimental and therapeutic medicine 2026 Feb;31(2):48
Microbiota-derived IPA protects against colitis by regulating intestinal HMGCS2-mediated ketogenesis to facilitate mucosal healing.
Zhang Y, Tu S, Shao X, Meng J, Zhang Z, Wei W, Jing X, Qin Z, Wu J, Xu W, Dong B, Gao J, Qu A, Chen S, Zhang L, Gong P, Shan B, Shi H, Zhu SJ
Nature communications 2026 Feb 6;17(1)
Nature communications 2026 Feb 6;17(1)
A microbiota-IPA axis facilitates intestinal stem cell-mediated regeneration in colitis through a Hopx-associated program.
Zhang Y, Meng J, Tu S, Ma L, Zhao X, Gao J, Wu J, Xu W, Chen S, Cheng H, Zhang L, Zhu SJ
Nature communications 2026 Feb 25;17(1)
Nature communications 2026 Feb 25;17(1)
Gut microbiota-derived trimethylamine N-oxide contributes to cardiomyocyte pyroptosis and cardiac injury via the tRF-Glu-ANT1-GSDMD axis.
Wang T, Ren W, Chen X, Wang X, Liu M, Zhang Y, Li Z, Wang Y, Song Z, Diao H
Cellular & molecular biology letters 2026 Feb 24;31(1)
Cellular & molecular biology letters 2026 Feb 24;31(1)
Adenosine from high-fat-diet-tolerant monkey-derived Limsolactobacillus reuteri MacFasB02 modulates cholesterol metabolism to alleviate hyperlipidemia and inflammation.
Jin Y, An HJ, Zheng TT, Li JJ, Gao JM, Zhong XL, Li BH, Liu YY, Zhuang XJ, Chen JH, Rao JH
NPJ science of food 2026 Feb 20;10(1)
NPJ science of food 2026 Feb 20;10(1)
Methanobrevibacter smithii activates immune microenvironment of intestinum tenue in a mouse model.
Jin M, Hu J, Tian C, Wu H, Wang B, Wang Y, Yang X, Ma C, Li F
Archives of microbiology 2026 Feb 19;208(4):199
Archives of microbiology 2026 Feb 19;208(4):199
Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a (-/-) mice.
Liu K, Zhang X, Li FZ, Zheng PY, Mi Y
World journal of gastrointestinal oncology 2026 Feb 15;18(2):114161
World journal of gastrointestinal oncology 2026 Feb 15;18(2):114161
A 4-guanidinobutanoic acid-SLC36A1 axis drives a microbiota‒host feedback loop to regulate intestinal homeostasis.
Yang J, Xiao Y, Cui J, Song R, Ma W, Liu J, Miao C, Sun X, Kong X, Zhang ZS, Zhou L, Yao Z, Wang Q
Gut microbes 2026 Dec 31;18(1):2639216
Gut microbes 2026 Dec 31;18(1):2639216
Xanthoxylin alleviates dextran sulfate sodium (DSS)-induced colitis by targeting macrophage infiltration via the tumor necrosis factor (TNF) /nuclear factor-kappa B (NF-κB) signaling pathway.
Chen Y, Chen Z, Li J, Zhao R, Chen Q, Zhong C, Lu M, Shi Y, Wang L, Bao L, Zuo Z, Mao X, Wu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157971
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157971
Dihydroartemisinin facilitates intestinal mucosal healing in inflammatory bowel disease by targeting 11βHSD-1 to reprogram macrophage metabolism.
Du X, Liu L, Zhang Y, Zhang B, Yang L, Chu M, Zhou L, Li Y, Zhu J, Dong K, Su X, Yang Q, Chen Y, Kan X, Han J, Zhu X, Xu J, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157774
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157774
Sex-Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu-erh Tea.
Li Y, Kuang J, Zheng D, Wang J, Ge K, Qu C, Zheng X, Ren Z, Huang F, Zhao M, Sun Y, Zhang H, Ding K, Xia X, Tang Y, Liu L, Zhou J, Gao F, Ma X, Xu Y, Xie G, Zhao A, Jia W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 16;:e19337
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 16;:e19337
Effects and mechanisms of nobiletin on gut motility by coordinating bile acid signaling via dual ileal-colonic axes in STC model mice.
Wang D, Zhu H, Zhou H, Li X, Zhao B, Zhu Y, Chu Y, Han Q
The Journal of nutritional biochemistry 2026 Apr 15;155:110385
The Journal of nutritional biochemistry 2026 Apr 15;155:110385
Polydisperse polystyrene microplastics exacerbate colitis through gut microbiota-butyrate-PPARγ axis disruption in mice.
Zhai Z, Yang Y, Xu Y, Fu Q, Chen S, Wu Z
Journal of hazardous materials 2026 Apr 1;507:141722
Journal of hazardous materials 2026 Apr 1;507:141722
Atlas of innate immune responses to experimental cholera and IL22 treatment demonstrates protection by mucus-secreting cells.
Suzuki M, Hasegawa Y, Zhang H, Liang Z, Tie G, Shivdasani RA, Waldor MK
bioRxiv : the preprint server for biology 2026 Apr 1;
bioRxiv : the preprint server for biology 2026 Apr 1;
Luteolin improves precancerous conditions of the gastric mucosa by binding STAT3 and inhibiting LCN2 expression.
Hao X, Yuan S, Ning J, Zhou Y, Lang Y, Han X, Meng Q, Xiong Y, Cui R, Gong Y, Ma C, Xu W, Wang Y, Guo X, Wang C, Zhang J, Fu W, Ding S
International journal of biological sciences 2025;21(8):3397-3415
International journal of biological sciences 2025;21(8):3397-3415
FMO5 Plays a Sex-specific Role in Goblet Cell Maturation and Mucus Barrier Formation.
Schaller ML, Sykes MM, Mecano J, Solanki S, Huang W, Rebernick RJ, Beydoun S, Wang E, Bugarin-Lapuz A, Shah YM, Leiser SF
Cellular and molecular gastroenterology and hepatology 2025;19(11):101591
Cellular and molecular gastroenterology and hepatology 2025;19(11):101591
Gegen Qinlian Decoction Ameliorated DSS-Induced Colitis by Attenuating Inflammation, Restoring Intestinal Mucosal Barrier and Modulating Gut Microbiota.
Wang Y, Yan R, Ye L, Tang C, Zhou H, Zhao G
Journal of inflammation research 2025;18:8065-8084
Journal of inflammation research 2025;18:8065-8084
Wuda Granule Alleviates DSS-Induced Colitis in Mice by Inhibiting Inflammation, Protecting Intestinal Barrier and Reducing Oxidative Stress Through Nrf2/Keap1/HO-1 Pathway.
Wang T, Ou Y, Xiong W, Luo L, Xu Y, Chen G, Peng Y, Chen Y, Zeng H, Yu Y, Tang H, Yao H, Wang W
Journal of inflammation research 2025;18:7301-7321
Journal of inflammation research 2025;18:7301-7321
Dahuang gancao dandelion decoction regulates intestinal flora and inhibits NF-κB/ARA signaling pathway to alleviate ulcerative colitis.
Malajiang X, Shen WE, Aersilan A, Liu M, Liang Y, Wang S, Abula S, Wusiman A
Frontiers in immunology 2025;16:1735021
Frontiers in immunology 2025;16:1735021
Lily polysaccharides alleviate colitis through the microbiota-N8-acetylspermidine-cGAS-STING signaling axis.
Wu Y, Wan X, Hou L, Zhang H, Wang J, Wu K, Shao J, Song Z
Frontiers in microbiology 2025;16:1686902
Frontiers in microbiology 2025;16:1686902
Lyophyllum decastes-derived polysaccharides alleviate DSS-induced colitis in mice by suppressing inflammation, enhancing intestinal barrier integrity, and restoring gut microbiota homeostasis.
Ghaleb E, Alioui Y, Yazeed J, Wahan N, Bashah A, Al-Waqeerah A, Atta A, Sun Y, Xin Y, Wang L, Feng B, Mao W
Frontiers in pharmacology 2025;16:1644325
Frontiers in pharmacology 2025;16:1644325
Proteus mirabilis exacerbates ulcerative colitis by inhibiting mucin production.
Jiang Z, Li P, Qiu K, Liao Y, Chen X, Xuan J, Wang F, Ma H, Wang Y, Zhu M
Frontiers in microbiology 2025;16:1556953
Frontiers in microbiology 2025;16:1556953
Preclinical evaluation of 6-Gingerol in modulating gut microbiota and SCFAs to mitigate Clostridium difficile-associated diarrhea in mice.
Ma FZ, Zhu L, Li M, Tang ZW, Yu XH, Zhang CE, Ma ZJ
Frontiers in chemistry 2025;13:1635781
Frontiers in chemistry 2025;13:1635781
Vespa orientalis pupae peptide hydrolysates modulate NF-κB signaling in LTA-induced pneumonia from clinical Enterococcus faecalis isolates: implications for gut microbiota.
Rahman MU, Ilyas M, Atta A, Alioui Y, Ali S, Ullah H, Ali M, Deng T, Farooqui NA, Ma R, Abusidu M, Wang J, Wang L, Xin Y
Frontiers in nutrition 2025;12:1651499
Frontiers in nutrition 2025;12:1651499
Ovotransferrin ameliorated intestinal barrier dysfunction in DSS-induced ulcerative colitis mice via inhibition of PI3K-Akt/MAPK signaling pathways and modulation of tissue metabolism.
Zheng D, Ma L, Xin X, Gao Y, Dong S, Huang Y, Wu J, Huo J, Li S
International journal of biological macromolecules 2025 Sep;321(Pt 1):146274
International journal of biological macromolecules 2025 Sep;321(Pt 1):146274
Metal-Organic Framework-Remodeled Gut Microbiota Alleviates Colonic Inflammation via Selective Modulation of Roseburia intestinalis.
Hu H, Su X, Dong Q, Yuan S, Ding S, Liu J, Xu B, Tu L, Liu X, Cao Y, Wang X, Yang G, Guo W, Fu S, Chao D
ACS nano 2025 Sep 2;19(34):31107-31125
ACS nano 2025 Sep 2;19(34):31107-31125
Structural Variations in Ulcerative Colitis-associated Escherichia coli Reduce Fructose Utilization and Aggravate Inflammation Under High-Fructose Diet.
Wu X, Li Y, Li P, Lu G, Wu J, Wang Z, Wen Q, Cui B, Wang J, Zhang F
Gastroenterology 2025 Oct;169(5):909-924
Gastroenterology 2025 Oct;169(5):909-924
Lychee Fermented by Mixed Probiotic Strains Alleviates D-Galactose-Induced Skeletal Muscle and Intestinal Aging in Mice.
Han H, Tao J, Bai X, Jing Y, Zhai Z, Luo J, Zhang W, Gan D, Hao Y
Foods (Basel, Switzerland) 2025 Oct 29;14(21)
Foods (Basel, Switzerland) 2025 Oct 29;14(21)
Enhancement of Intestinal Barrier Function by Butyryl-Fructooligosaccharides via Microbiota-Host Interactions in Colonic Organoid Models.
Li H, Liu L, Liu J, Zheng H, Long J, Wang J, Ku S, Weng M, Kang S
Journal of agricultural and food chemistry 2025 Oct 15;73(41):26141-26153
Journal of agricultural and food chemistry 2025 Oct 15;73(41):26141-26153
Nuclear receptor Nr1d1 links sleep deprivation to intestinal homeostasis via microbiota-derived taurine.
Wang Z, Zhou L, Zheng Y, Zhong X, Huang R, Sun W, Wang S, Li W
Journal of translational medicine 2025 Oct 15;23(1):1106
Journal of translational medicine 2025 Oct 15;23(1):1106
Resveratrol attenuates Citrobacter rodentium-infected colitis by remodeling the gut microbiota structure and inhibiting CD4(+) cell activation in mice.
Li J, Feng X, Jing Y, Qian H, Ji Y, Hao Y, Zhai Z
Food & function 2025 Oct 13;16(20):8128-8139
Food & function 2025 Oct 13;16(20):8128-8139
ALKBH8-mediated codon-specific translation promotes colorectal tumorigenesis.
Qian Y, Wu C, Wei S, Yan S, Peng J, Yu L, Gao Y, Hou J, Yu W, Chen Z, Zhang J, Gao X
Nature communications 2025 Oct 13;16(1):9075
Nature communications 2025 Oct 13;16(1):9075
Silymarin ameliorates diet-induced gallstone formation by regulating gut microbiota-derived GCDCA to suppress ferroptosis-ROS-NFκB signaling pathway.
Wang Q, Han C, Zheng Y, Liu X, Lv Z, Du Z, Liu T, Hao C, Meng X, Li T, Xue D
Free radical biology & medicine 2025 Nov;239:496-512
Free radical biology & medicine 2025 Nov;239:496-512
Lactiplantibacillus plantarum BD7807 ameliorates high-fat diet-induced lipid metabolic disorders and intestinal dysfunction via SCFAs-GPR43 pathway.
Li T, Wu J, Xia S, Yang H, Mu H, Zhu Y, Wu R, Liu Z
Food research international (Ottawa, Ont.) 2025 Nov;220:117108
Food research international (Ottawa, Ont.) 2025 Nov;220:117108
Yuzhi Zhixue Granules regulate the JAK/STAT pathway to affect T-cell differentiation in the colon of ulcerative colitis.
Zhang Y, He C, Zhao Y, Jiang M, Yao J, Cheng G, Niu D, Zeng Z, Dai E, Liu R, Shang G, Qu X, Kong H, Zhang Y, Qu H, Zhao Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157198
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157198
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Tao X, Gao Y, Jin Z, Lu S, Li Z, Guo S, Fan Q, Li J, Qiao C, Lei H, Zhang Z, Zhao C, Wu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Chronic psychological stress-orchestrated glial-ILC3 circuit exacerbates intestinal inflammation and depression.
Zhang Z, Ren S, Fan X, Chen H, Chen J, Wang X, Zong H, Zhang S, Zhao T, Sun Y, Pang R, Song W, Zhang W, Wang B, Chen Z, Ge L
Brain, behavior, and immunity 2025 Nov;130:106118
Brain, behavior, and immunity 2025 Nov;130:106118
Novel Role of Gut-Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure.
Zhou L, Wang C, Gao J, Wu X, Li G, Jiang X, Xia Y, Zhang J, Lv B, Zhao F, Zhang H, Pi H, Qiu J, Xu S, Zou Z, Chen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(42):e11895
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(42):e11895
Functional and morphological characterisation of human colonoid-derived monolayers under inflammatory conditions.
Parente IA, Chiara L, Flammini L, Viglioli M, Vacondio F, Gaiani F, de'Angelis GL, Pagano Mariano M, La Monica S, Barocelli E, Bertoni S
International journal of pharmaceutics 2025 Nov 30;685:126228
International journal of pharmaceutics 2025 Nov 30;685:126228
Effects of Abrus cantoniensis capsule on gut microbiota and intestinal barrier in mice infected with alveolar echinococcosis.
Cao D, Huang W, Pang M, Qin Y, Li J, Li D, Mo G, Chen G, Fan H, Peng X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157516
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157516
Autism-Associated Gut Microbiota-Derived Enterococcus facium Modulates Gut-Brain Axis Function and Behavior in Mice.
Ma R, Ullah H, Bohlooli FS, Wen Y, Xin Y, Wang J, Lu S, Wang L
Pathogens (Basel, Switzerland) 2025 Nov 21;14(12)
Pathogens (Basel, Switzerland) 2025 Nov 21;14(12)
Berberine ameliorates high-fat diet-induced metabolic disorders through promoting gut Akkermansia and modulating bile acid metabolism.
Hang WJ, Yin R, Kang XW, He L, Cao X, Chen J
Chinese medicine 2025 Nov 17;20(1):190
Chinese medicine 2025 Nov 17;20(1):190
Antibacterial hyaluronic acid hydrogel with sustained release of larazotide as effective colitis treatment.
Yu F, Chen Y, Ouyang S, Tong B, Jiang Z, Wang J, Ding B, Mao K, Wu W, Xu H
Journal of controlled release : official journal of the Controlled Release Society 2025 Nov 10;387:114205
Journal of controlled release : official journal of the Controlled Release Society 2025 Nov 10;387:114205
Proline rich-39 (PR-39) antimicrobial protein alleviated lipopolysaccharide-induced intestinal barrier dysfunction in piglets by altering intestinal flora associated bile acid metabolism and in turn regulating TGR-5/NF-κB/MLCK/MLC pathway.
Liu Z, Qin X, Zhang B, Nong K, Chen W, Yang Z, Lang W, Liu X, Li L, Wang X, Shi H, Zhang H
International journal of biological macromolecules 2025 May;307(Pt 1):141930
International journal of biological macromolecules 2025 May;307(Pt 1):141930
β-1,3-glucans from Euglena Gracilis protects against ulcerative colitis via modulating the gut barrier, T-cell immunity and gut microbiota.
Guo B, Zhang W, Zou J, Sun L, Dong N, Liu B
International journal of biological macromolecules 2025 May;305(Pt 2):141288
International journal of biological macromolecules 2025 May;305(Pt 2):141288
ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity.
Zhou S, Hua S, Chen X, Ni M, Liu J, Wang Y, Wu W, Ding A, Qin Z, Yang X, Chen X, Zhu B, Wu H
Chinese medicine 2025 May 25;20(1):68
Chinese medicine 2025 May 25;20(1):68
Evaluation of Indigo Naturalis Prepared Using a Novel Method: Therapeutic Effects on Experimental Ulcerative Colitis in Mice.
Xu X, Lin L, Ning W, Zhou X, Ullah A, Yang H, Wu X, Diao Y
Pharmaceutics 2025 May 20;17(5)
Pharmaceutics 2025 May 20;17(5)
Polygonatum cyrtonema Hua polysaccharide alleviates ulcerative colitis via gut microbiota-independent modulation of inflammatory immune response.
Shi JY, Wang YJ, Bao QW, Qin YM, Li PP, Wu QQ, Xia CK, Wu DL, Xie SZ
Carbohydrate polymers 2025 May 15;356:123387
Carbohydrate polymers 2025 May 15;356:123387
Huangqin decoction alleviated irinotecan-induced diarrhea by inhibiting endoplasmic reticulum stress through activating AMPK/mTOR-mediated autophagy.
He Y, Feng L, Gao Y, Wang Y, Yang C, Han S, Ren Y, Zhai Y, Nie K
Journal of ethnopharmacology 2025 May 12;347:119790
Journal of ethnopharmacology 2025 May 12;347:119790
A novel scheme for non-invasive drug delivery with a magnetically controlled drug delivering capsule endoscope.
Wang W, Zhang K, Ming F, Chen B, Zhang H, Wang Z, Jiang X, Zhang H, Shang G, Bao Y, Peng H, Liu S, Ling X, Li W, Zhu H, Zhang Y, Cai S, Ding Z, Lin R
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113591
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113591
Runchangningshen paste activates NLRP6 inflammasome-mediated autophagy to stimulate colonic mucin-2 secretion and modulates mucosal microbiota in functional constipation.
Liu XJ, Ye-Er-Tai YL, Jia YB, Wu CH, Wang XX, Yang KM, Yao X, Ling JH
World journal of gastroenterology 2025 Mar 7;31(9):102256
World journal of gastroenterology 2025 Mar 7;31(9):102256
Multi-omics approaches reveal the therapeutic mechanism of Naoxintong capsule against ischemic stroke.
Li Y, Zhang J, Lei Y, Chang M, Xu J, Tang S
Journal of ethnopharmacology 2025 Mar 13;343:119435
Journal of ethnopharmacology 2025 Mar 13;343:119435
Bifidobacterium longum BL300 alleviates DSS-induced Colitis by promoting IgA-mediated Gut Microbiota homeostasis.
Jin H, Wang H, Feng X, Ma X, Zhai Z, Hao Y
Food & function 2025 Jun 3;16(11):4303-4314
Food & function 2025 Jun 3;16(11):4303-4314
Dual Role of NRF2 in Pancreatic Precursor Lesions.
Ichimiya S, Ahn SS, Dixon MS, O'Sullivan JP, DeVine LC, Chen A, Yamamoto T, Oda Y, Nakamura M, Chio IIC
Cancer research communications 2025 Jun 1;5(6):945-959
Cancer research communications 2025 Jun 1;5(6):945-959
Music intervention mitigates LPS-induced gut barrier disruption and immune stress in broilers via TLR4/NF-κB regulation.
Jin S, Wang H, Gong H, Guo L, Zhang H, Zhang J, Chang Q, Li J, Zhang R, Bao J
Poultry science 2025 Jul;104(7):105189
Poultry science 2025 Jul;104(7):105189
Engineered tumor microspheres via microfluidics and decellularized extracellular matrix for high-throughput organoid-based drug screening.
Jin J, Chen W, Li J, Yang J, Dai R, Tang J, Li M, Chen Y, Zhang C, Liu J
Biofabrication 2025 Jul 25;17(4)
Biofabrication 2025 Jul 25;17(4)
Acid-Enzyme Derived Agarotriose Facilitates Anti-Inflammatory Activity for Dextran Sulfate Sodium-Induced Colitis Alleviation as a Food Supplement.
Cai Y, Chen S, Gu H, Wang D, Shi Y, Jing Y, Li Z, Li C, Ban X
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18329-18345
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18329-18345
Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice.
Wu Y, Zhang Y, Yu Y, Wang X, Zhen Z, Yuan Y, Xie B, Han M, Wang M, Zhang X, Sun X, Wen X, Hashimoto K, Shang Y, Yuan S, Zhang J
Nature communications 2025 Jul 23;16(1):6779
Nature communications 2025 Jul 23;16(1):6779
Agrocybe cylindracea Polysaccharides Ameliorate DSS-Induced Colitis by Restoring Intestinal Barrier Function and Reprogramming Immune Homeostasis via the Gut-Liver Axis.
Atta A, Naveed M, Rahman MU, Alioui Y, Ansari I, Ali S, Ghaleb E, Farooqui NA, Abusidu M, Xin Y, Feng B
International journal of molecular sciences 2025 Jul 16;26(14)
International journal of molecular sciences 2025 Jul 16;26(14)
Multi-Omics Integration Reveals Gut Microbiota-Bile Acid Crosstalk Underlying Baizhu Shaoyao Decoction's Therapeutic Efficacy in Weaning Stress of Piglets.
Wei Y, Han C, Chen Z, Wang C, Liu M, Fan Y, Lv J, Hao Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70828
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70828
Cimicifuga heracleifolia kom. Attenuates ulcerative colitis through the PI3K/AKT/NF-κB signaling pathway.
Wu XY, Dong QW, Zhang YB, Li JX, Zhang MQ, Zhang DQ, Cui YL
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118892
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118892
Gut bacterial L-lysine alters metabolism and histone methylation to drive dendritic cell tolerance.
Tang Q, Fan G, Peng X, Sun X, Kong X, Zhang L, Zhang C, Liu Y, Yang J, Yu K, Miao C, Yao Z, Li L, Zhang ZS, Wang Q
Cell reports 2025 Jan 28;44(1):115125
Cell reports 2025 Jan 28;44(1):115125
Lentinan's effect on gut microbiota and inflammatory cytokines in 5-FU-induced mucositis mice.
Zhang X, Wang L, Khan AI, Rehman AU, Khinsar KH, Xin Y
AMB Express 2025 Jan 22;15(1):11
AMB Express 2025 Jan 22;15(1):11
Targeting Catenibacterium mitsuokai with icariin modulates gut microbiota and improves hepatic lipid metabolism in intrauterine growth restriction.
Wei Y, Mao J, Tang W, Ma Y, Li J, Su S, Ni Z, Wu J, Liu D, Wang H
The ISME journal 2025 Jan 2;19(1)
The ISME journal 2025 Jan 2;19(1)
Photo-Crosslinking Hydrogel Based on Porcine Small Intestinal Submucosa Decellularized Matrix/Fish Collagen/GelMA for Culturing Small Intestinal Organoids and Repairing Intestinal Defects.
Jia Z, Wang Z
International journal of molecular sciences 2025 Jan 14;26(2)
International journal of molecular sciences 2025 Jan 14;26(2)
Neohesperidin Mitigates High-Fat-Diet-Induced Colitis In Vivo by Modulating Gut Microbiota and Enhancing SCFAs Synthesis.
Lu K, Shan S, Zeng Y, Yang G
International journal of molecular sciences 2025 Jan 10;26(2)
International journal of molecular sciences 2025 Jan 10;26(2)
LGR4 promotes proliferation and homing via activation of the NF‑κB signaling pathway in multiple myeloma.
He N, Yang Q, Li Z, Guo J, Kuang C, Zhu Y, Liu X, Chen X, Shi F, Feng X, An G, Zhang G, Zhou W
International journal of oncology 2025 Feb;66(2)
International journal of oncology 2025 Feb;66(2)
Organoid-based in vitro system and reporter for the study of Cryptosporidium parvum sexual reproduction.
Korwin-Mihavics BR, Dews EA, Miller P, Cameron A, Martorelli di Genova B, Huston CD
bioRxiv : the preprint server for biology 2025 Feb 3;
bioRxiv : the preprint server for biology 2025 Feb 3;
Ligustilide improves functional constipation by non-covalently activating TRPA1 in colon tissue.
Zhang K, Luan G, Liu W, Shen F, Jiang M, Bai G
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119018
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119018
Terpine-4-ol alleviates lipopolysaccharide-induced intestinal injury in weaned piglets by regulating intestinal epithelial cell homeostasis via the Wnt/β-catenin signaling pathway.
Dong L, Zhou Y, Wang M, Yuan Q, Qiu G, Liu J, Wang H, Wu A, Yu L, Chen D
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Dec;23:178-190
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Dec;23:178-190
Novel role of FTO in regulation of gut-brain communication via Desulfovibrio fairfieldensis-produced hydrogen sulfide under arsenic exposure.
Chen R, Chai X, Zhang Y, Zhou T, Xia Y, Jiang X, Lv B, Zhang J, Zhou L, Tian X, Wang R, Mao L, Zhao F, Zhang H, Hu J, Qiu J, Zou Z, Chen C
Gut microbes 2025 Dec;17(1):2438471
Gut microbes 2025 Dec;17(1):2438471
Dietary iron attenuates Clostridioides difficile infection via modulation of intestinal immune response and gut microbiota.
Li X, Wu X, Zang W, Zhou Z, Cui W, Chen Y, Yang H
Virulence 2025 Dec;16(1):2529454
Virulence 2025 Dec;16(1):2529454
The Therapeutic Effect and Mechanism of Lactobacillus gardneri on Nonalcoholic Fatty Liver Disease.
Zhu K, Xiang J, Lu F, Wang J, Zhang Y, Feng H, Xiang X
Journal of microbiology and biotechnology 2025 Dec 29;35:e2501051
Journal of microbiology and biotechnology 2025 Dec 29;35:e2501051
Revealing the Immune and Inflammatory Mechanisms of Electroacupuncture in Male IBS Rats Through Multi-Omics Analysis.
Wang L, Chang X, Zhang L, Xu R, Chen L, Chen S, Yang Z
Neurogastroenterology and motility 2025 Dec 18;:e70185
Neurogastroenterology and motility 2025 Dec 18;:e70185
Integrative analysis of gut microbiome and serum metabolomics explores the therapeutic mechanism of tongfeng qingxiao prescription in treating gouty arthritis.
Huang X, Hu L, Sun W, Shao Z, Ma W, Yuan Q, Liu J, Wu D, Cheng L, Li H
Journal of pharmaceutical and biomedical analysis 2025 Dec 15;266:117121
Journal of pharmaceutical and biomedical analysis 2025 Dec 15;266:117121
Six Weeks of Moderate-Intensity Treadmill Exercise Improves Intestinal Barrier and Intestinal Inflammation in Parkinson's Disease Mice.
Li T, Zhou SY, Quan W, Zhou Y, Wu J, Zhao LP, Qiao CM, Zhao WJ, Cui C, Shen YQ
Molecular neurobiology 2025 Aug;62(8):10779-10791
Molecular neurobiology 2025 Aug;62(8):10779-10791
Gut microbiota promote the propagation of pathologic α-syn from gut to brain in a gut-originated mouse model of Parkinson's disease.
Wu J, Li CS, Huang WY, Zhou SY, Zhao LP, Li T, Li MA, Zhang MX, Qiao CM, Zhao WJ, Cui C, Shen YQ
Brain, behavior, and immunity 2025 Aug;128:152-169
Brain, behavior, and immunity 2025 Aug;128:152-169
Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409-Ube2k-Foxp3 Axis in Regulatory T Cells.
Xie J, Du L, Lu Y, Guo X, Zhou X, Tong Y, Shen B, Yu X, Guo F, Yu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e04214
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e04214
Banxia Xiexin Decoction inhibits colitis-associated colorectal cancer development by modulating STAT3 signaling and gut microbiota.
Yue Y, Su L, Wang Y, Li X, Xiao X, Xie J, Yan S
Chinese herbal medicines 2025 Apr;17(2):380-391
Chinese herbal medicines 2025 Apr;17(2):380-391
Gut microbiota contributes to protection against porcine deltacoronavirus infection in piglets by modulating intestinal barrier and microbiome.
Zhang Y, Si L, Shu X, Qiu C, Wan X, Li H, Ma S, Jin X, Wei Z, Hu H
Microbiome 2025 Apr 7;13(1):93
Microbiome 2025 Apr 7;13(1):93
Gut microbiota-derived UDCA enhanced by metformin inhibits FXR to activate autophagy against MCD diet-induced NAFLD in mice.
Liu X, Sun H, Han Q, Wang Z, Zeng J, Liu J, Ou S, Jin K, Shao Y, Li D, Gao Z, Wang F
International immunopharmacology 2025 Apr 24;153:114471
International immunopharmacology 2025 Apr 24;153:114471
Colon-Targeted Mucoadhesive PLGA Microspheres Loaded with Ramulus Mori Alkaloids for Enhanced Water-Soluble Drug Delivery in Ulcerative Colitis Treatment.
Wang M, Jiang Y, Chen Z, Jiang D, Jiang X, Ye J, Wang H, Liu Y
Molecules (Basel, Switzerland) 2025 Apr 23;30(9)
Molecules (Basel, Switzerland) 2025 Apr 23;30(9)
Green Tea Ameliorates Depression-Like Behavior and Cognitive Impairment Induced by High-Fat Diet and Chronic Mild Stress.
Fan M, Jiang Y, Cai C, Wang Z, Chen L, Hu S, Zhang X, Yin H, Qian Z, Huang S, Yang J
Phytotherapy research : PTR 2025 Apr 17;
Phytotherapy research : PTR 2025 Apr 17;
Polysaccharides derived from golden mushroom (Cantharellus cibarius Fr.) modulate gut microbiota and enhance intestinal barrier function to ameliorate dextran sulfate sodium-induced colitis in mice.
Alioui Y, Ullah H, Ali S, Rahman MU, Elkharti M, Farooqui NA, Rehman AU, Ilyas M, Alsholi DM, Siddiqi NZ, Ali M, Wang L, Xin Y
Frontiers in pharmacology 2024;15:1498625
Frontiers in pharmacology 2024;15:1498625
Modified Gegen Qinlian Decoction modulated the gut microbiome and bile acid metabolism and restored the function of goblet cells in a mouse model of ulcerative colitis.
Huang J, Zhang J, Wang F, Tang X
Frontiers in immunology 2024;15:1445838
Frontiers in immunology 2024;15:1445838
Btbd8 deficiency reduces susceptibility to colitis by enhancing intestinal barrier function and suppressing inflammation.
Yang X, He Z, Dong Q, Nai S, Duan X, Yu J, Zhao N, Du X, Chen L
Frontiers in immunology 2024;15:1382661
Frontiers in immunology 2024;15:1382661
Fmo5 plays a sex-specific role in goblet cell maturation and mucus barrier formation.
Schaller ML, Sykes MM, Mecano J, Solanki S, Huang W, Rebernick RJ, Beydoun S, Wang E, Bugarin-Lapuz A, Shah YM, Leiser SF
bioRxiv : the preprint server for biology 2024 Sep 25;
bioRxiv : the preprint server for biology 2024 Sep 25;
Procyanidin B1 and p-coumaric acid from whole highland barley ameliorated HFD-induced impaired glucose tolerance via small intestinal barrier and hepatic glucose metabolism.
Liu Z, Yang Y, Xu Y, Zhang Z, Tang R, Liu J, Jiang H, Zhao R
Food & function 2024 Sep 16;15(18):9272-9283
Food & function 2024 Sep 16;15(18):9272-9283
Bitter-tasting drugs tune GDF15 and GLP-1 expression via bitter taste or motilin receptors in the intestine of patients with obesity.
Wang Q, Farhadipour M, Thijs T, Ruilova Sosoranga E, Van der Schueren B, Ceulemans LJ, Deleus E, Lannoo M, Tack J, Depoortere I
Molecular metabolism 2024 Oct;88:102002
Molecular metabolism 2024 Oct;88:102002
Protective properties of Ophiopogonin D in DSS-induced colitis: insights into microbiota modulation.
Zhang T, Guo Z, Cheng X, Xia R, Lai S, Liao L
Inflammopharmacology 2024 Oct;32(5):3553-3570
Inflammopharmacology 2024 Oct;32(5):3553-3570
Combined effects of TiO(2) nanoparticle and fipronil co-exposure on microbiota in mouse intestine.
Wang C, Liu Y, He Y, Li J, Cao Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114931
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114931
ADORA3 activation promotes goblet cell differentiation via enhancing HMGCS2-mediated ketogenesis in ulcerative colitis.
Zeng X, Hu Y, Qiao S, Cao X, Dai Y, Wu F, Wei Z
International immunopharmacology 2024 Oct 25;140:112729
International immunopharmacology 2024 Oct 25;140:112729
CTPAD: an interactive web application for comprehensive transcriptomic profiling in allergic diseases.
Zhou S, Huang W, Liu Y, Luo P, Lin A, Yang H, Qiu Q
Journal of translational medicine 2024 Oct 14;22(1):935
Journal of translational medicine 2024 Oct 14;22(1):935
Dietary nitrate maintains intestinal epithelia homeostasis in aged mice.
Wang X, Liu H, Yue M, Wang J, Zhang C, Qin L, Wang S, Hu L
Biogerontology 2024 Nov;25(6):1171-1187
Biogerontology 2024 Nov;25(6):1171-1187
Microbiota-derived succinic acid mediates attenuating effect of dietary tomato juice supplementation on steatohepatitis through enhancing intestinal barrier.
Song X, Sun J, Yue Y, Li D, Chen F
Food research international (Ottawa, Ont.) 2024 Nov;196:115123
Food research international (Ottawa, Ont.) 2024 Nov;196:115123
Alginate Oligosaccharides Enhance Gut Microbiota and Intestinal Barrier Function, Alleviating Host Damage Induced by Deoxynivalenol in Mice.
Mi J, Tong Y, Zhang Q, Wang Q, Wang Y, Wang Y, Lin G, Ma Q, Li T, Huang S
The Journal of nutrition 2024 Nov;154(11):3190-3202
The Journal of nutrition 2024 Nov;154(11):3190-3202
Lycium barbarum polysaccharide remodels colon inflammatory microenvironment and improves gut health.
Li R, Yang P, Liu B, Ye Z, Zhang P, Li M, Gong Y, Huang Y, Yang L, Li M
Heliyon 2024 May 30;10(10):e30594
Heliyon 2024 May 30;10(10):e30594
POFUT1 and PLAGL2 are characteristic markers of mucinous colorectal cancer associated with MUC2 expression.
Monno M, Ogiri M, Seishima R, Suzuki Y, Hattori K, Matsui S, Shigeta K, Okabayashi K, Kitagawa Y
Cell biochemistry and function 2024 Mar;42(2):e3989
Cell biochemistry and function 2024 Mar;42(2):e3989
Social isolation induces intestinal barrier disorder and imbalances gut microbiota in mice.
Wang Y, Ullah H, Deng T, Ren X, Zhao Z, Xin Y, Qiu J
Neuroscience letters 2024 Mar 15;826:137714
Neuroscience letters 2024 Mar 15;826:137714
Prevotella histicola ameliorates DSS-induced colitis by inhibiting IRE1α-JNK pathway of ER stress and NF-κB signaling.
Fan X, Lu Q, Jia Q, Li L, Cao C, Wu Z, Liao M
International immunopharmacology 2024 Jun 30;135:112285
International immunopharmacology 2024 Jun 30;135:112285
Bound Polyphenols of Oat Bran Released by Gut Microbiota Mitigate High Fat Diet-Induced Oxidative Stress and Strengthen the Gut Barrier via the Colonic ROS/Akt/Nrf2 Pathway.
Zhang Y, Bai B, Huang K, Li S, Cao H, Guan X
Journal of agricultural and food chemistry 2024 Jun 12;72(23):13099-13110
Journal of agricultural and food chemistry 2024 Jun 12;72(23):13099-13110
PIM1-HDAC2 axis modulates intestinal homeostasis through epigenetic modification.
Yang J, Xiao Y, Zhao N, Pei G, Sun Y, Sun X, Yu K, Miao C, Liu R, Lv J, Chu H, Zhou L, Wang B, Yao Z, Wang Q
Acta pharmaceutica Sinica. B 2024 Jul;14(7):3049-3067
Acta pharmaceutica Sinica. B 2024 Jul;14(7):3049-3067
Impact of hepatocyte growth factor on the colonic morphology and gut microbiome in short bowel syndrome rat model.
Sugita K, Yano K, Onishi S, Tabata Y, Iwamoto Y, Ogata M, Takada L, Kedoin C, Murakami M, Harumatsu T, Matsukubo M, Kawano T, Muto M, Kumagai K, Ido A, Kaji T, Ieiri S
Pediatric surgery international 2024 Jul 13;40(1):185
Pediatric surgery international 2024 Jul 13;40(1):185
Leveraging Temporal Wnt Signal for Efficient Differentiation of Intestinal Stem Cells in an Organoid Model.
Yang L, Wang X, Zhao G, Deng L, Yin X
Stem cells and development 2024 Jan;33(1-2):11-26
Stem cells and development 2024 Jan;33(1-2):11-26
Infant feces-derived Lactobacillus gasseri FWJL-4 mitigates experimental necrotizing enterocolitis via acetate production.
Pan LL, Sun Y, Dong X, Ren Z, Li B, Yang P, Zhang L, Sun J
Gut microbes 2024 Jan-Dec;16(1):2430541
Gut microbes 2024 Jan-Dec;16(1):2430541
The protective effect of Schisandra chinensis (Turcz.) Baill. polysaccharide on DSS-induced ulcerative colitis in mice via the modulation of gut microbiota and inhibition of NF-κB activation.
Guo X, Liu L, Zhao W, Li X, Wang X, Ning A, Cao J, Zhang W, Cao L, Zhong M
Journal of the science of food and agriculture 2024 Jan 15;104(1):196-206
Journal of the science of food and agriculture 2024 Jan 15;104(1):196-206
Multi-omics reveals the protective effects of curcumin against AFB1-induced oxidative stress and inflammatory damage in duckling intestines.
Jiang X, Liu H, You Y, Zhong G, Ruan Z, Liao J, Zhang H, Pan J, Tang Z, Hu L
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2024 Feb;276:109815
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2024 Feb;276:109815
peu-MIR2916-p3-enriched garlic exosomes ameliorate murine colitis by reshaping gut microbiota, especially by boosting the anti-colitic Bacteroides thetaiotaomicron.
Wang X, Liu Y, Dong X, Duan T, Wang C, Wang L, Yang X, Tian H, Li T
Pharmacological research 2024 Feb;200:107071
Pharmacological research 2024 Feb;200:107071
Fucoidan alleviated dextran sulfate sodium-induced ulcerative colitis with improved intestinal barrier, reshaped gut microbiota composition, and promoted autophagy in male C57BL/6 mice.
Li S, Qian Q, Yang H, Wu Z, Xie Y, Yin Y, Cui Y, Li X
Nutrition research (New York, N.Y.) 2024 Feb;122:1-18
Nutrition research (New York, N.Y.) 2024 Feb;122:1-18
Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway.
Zhang Y, Tu S, Ji X, Wu J, Meng J, Gao J, Shao X, Shi S, Wang G, Qiu J, Zhang Z, Hua C, Zhang Z, Chen S, Zhang L, Zhu SJ
Nature communications 2024 Feb 13;15(1):1333
Nature communications 2024 Feb 13;15(1):1333
Gut-Microbiota-Derived Butyric Acid Overload Contributes to Ileal Mucosal Barrier Damage in Late Phase of Chronic Unpredictable Mild Stress Mice.
Wang C, Qiu M, Wang S, Luo J, Huang L, Deng Q, Fang Z, Sun L, Gooneratne R
International journal of molecular sciences 2024 Dec 3;25(23)
International journal of molecular sciences 2024 Dec 3;25(23)
Terpinen-4-ol Improves the Intestinal Barrier Function of the Colon in Immune-Stressed Weaning Piglets.
Yu L, Qiu G, Yu X, Zhao J, Liu J, Wang H, Dong L
Animals : an open access journal from MDPI 2024 Dec 24;15(1)
Animals : an open access journal from MDPI 2024 Dec 24;15(1)
Berberine ameliorates dextran sulfate sodium -induced colitis through tuft cells and bitter taste signalling.
Yang Y, Li W, Sun K, Sun S, Zhang Y, Chen L, Ni Y, Hou M, Xu Z, Chen L, Ji M
BMC biology 2024 Dec 2;22(1):280
BMC biology 2024 Dec 2;22(1):280
Gut-derived memory γδ T17 cells exacerbate sepsis-induced acute lung injury in mice.
Xie B, Wang M, Zhang X, Zhang Y, Qi H, Liu H, Wu Y, Wen X, Chen X, Han M, Xu D, Sun X, Zhang X, Zhao X, Shang Y, Yuan S, Zhang J
Nature communications 2024 Aug 7;15(1):6737
Nature communications 2024 Aug 7;15(1):6737
1,25-Dihydroxyvitamin D Enhances the Regenerative Function of Lgr5(+) Intestinal Stem Cells In Vitro and In Vivo.
Shaikh NA, Liu C, Yin Y, Baylink DJ, Tang X
Cells 2024 Aug 31;13(17)
Cells 2024 Aug 31;13(17)
Faecalibacterium prausnitzii Supplementation Prevents Intestinal Barrier Injury and Gut Microflora Dysbiosis Induced by Sleep Deprivation.
Wang X, Li Y, Wang X, Wang R, Hao Y, Ren F, Wang P, Fang B
Nutrients 2024 Apr 9;16(8)
Nutrients 2024 Apr 9;16(8)
A commensal protozoan attenuates Clostridioides difficile pathogenesis in mice via arginine-ornithine metabolism and host intestinal immune response.
Yang H, Wu X, Li X, Zang W, Zhou Z, Zhou Y, Cui W, Kou Y, Wang L, Hu A, Wu L, Yin Z, Chen Q, Chen Y, Huang Z, Wang Y, Gu B
Nature communications 2024 Apr 2;15(1):2842
Nature communications 2024 Apr 2;15(1):2842
Ellagic acid alleviates TNBS-induced intestinal barrier dysfunction by regulating mucin secretion and maintaining tight junction integrity in rats.
Peng B, Xue L, Yu Q, Zhong T
International journal of food sciences and nutrition 2023;74(4):476-486
International journal of food sciences and nutrition 2023;74(4):476-486
Lactiplantibacillus plantarum L47 and inulin alleviate enterotoxigenic Escherichia coli induced ileal inflammation in piglets by upregulating the levels of α-linolenic acid and 12,13-epoxyoctadecenoic acid.
Cui L, Zeng H, Hou M, Li Z, Mu C, Zhu W, Hang S
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Sep;14:370-382
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Sep;14:370-382
Live and pasteurized Akkermansia muciniphila decrease susceptibility to Salmonella Typhimurium infection in mice.
Liu J, Liu H, Liu H, Teng Y, Qin N, Ren X, Xia X
Journal of advanced research 2023 Oct;52:89-102
Journal of advanced research 2023 Oct;52:89-102
Organoids transplantation attenuates intestinal ischemia/reperfusion injury in mice through L-Malic acid-mediated M2 macrophage polarization.
Zhang FL, Hu Z, Wang YF, Zhang WJ, Zhou BW, Sun QS, Lin ZB, Liu KX
Nature communications 2023 Oct 25;14(1):6779
Nature communications 2023 Oct 25;14(1):6779
The metabolite butyrate produced by gut microbiota inhibits cachexia-associated skeletal muscle atrophy by regulating intestinal barrier function and macrophage polarization.
Liu H, Xi Q, Tan S, Qu Y, Meng Q, Zhang Y, Cheng Y, Wu G
International immunopharmacology 2023 Nov;124(Pt B):111001
International immunopharmacology 2023 Nov;124(Pt B):111001
Bile Acid Derivatives Effectively Prevented High-Fat Diet-Induced Colonic Barrier Dysfunction.
Ma Y, Shan K, Huang Z, Zhao D, Zhang M, Ke W, Li C
Molecular nutrition & food research 2023 May;67(10):e2200649
Molecular nutrition & food research 2023 May;67(10):e2200649
A possible but unrecognized risk of acceptable daily intake dose triazole pesticides exposure-bile acid disturbance induced pharmacokinetic changes of oral medication.
Xu Y, Zhang Y, Tao Q, Sun Q, Zheng Y, Yin D, Yang Y
Chemosphere 2023 May;322:138209
Chemosphere 2023 May;322:138209
The protective effects of electroacupuncture on intestinal barrier lesions in IBS and UC model.
Liu S, Huang Q, Huang Q, Wang Y, Li S, Wang J, Wu Q
Scientific reports 2023 May 4;13(1):7276
Scientific reports 2023 May 4;13(1):7276
Shaoyao decoction restores the mucus layer in mice with DSS-induced colitis by regulating Notch signaling pathway.
Fang YX, Liu YQ, Hu YM, Yang YY, Zhang DJ, Jiang CH, Wang JH, Zhang J
Journal of ethnopharmacology 2023 May 23;308:116258
Journal of ethnopharmacology 2023 May 23;308:116258
A high-sucrose diet causes microbiota composition shift and promotes the susceptibility of mice to Salmonella Typhimurium infection.
Liu J, Liu H, Teng Y, Qin N, Ren X, Xia X
Food & function 2023 Mar 20;14(6):2836-2846
Food & function 2023 Mar 20;14(6):2836-2846
Single-cell transcriptomics reveals intestinal cell heterogeneity and identifies Ep300 as a potential therapeutic target in mice with acute liver failure.
Yin J, Zhao Z, Huang J, Xiao Y, Rehmutulla M, Zhang B, Zhang Z, Xiang M, Tong Q, Zhang Y
Cell discovery 2023 Jul 25;9(1):77
Cell discovery 2023 Jul 25;9(1):77
Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis.
Tian Z, Khan AI, Rehman AU, Deng T, Ma C, Wang L
Gut pathogens 2023 Jan 9;15(1):2
Gut pathogens 2023 Jan 9;15(1):2
Budget-Friendly Generation, Biochemical Analyses, and Lentiviral Transduction of Patient-Derived Colon Organoids.
Rigaux E, Chen JW, George F, Lemaire J, Bertrand C, Faugeras L, Fattaccioli A, Gilliaux Q, D'Hondt L, Michiels C, Renard HF, Zanin N
Current protocols 2023 Dec;3(12):e943
Current protocols 2023 Dec;3(12):e943
Impact of structurally diverse polysaccharides on colonic mucin O-glycosylation and gut microbiota.
Zhao T, Zhang Y, Nan L, Zhu Q, Wang S, Xie Y, Dong X, Cao C, Lin X, Lu Y, Liu Y, Huang L, Gong G, Wang Z
NPJ biofilms and microbiomes 2023 Dec 11;9(1):97
NPJ biofilms and microbiomes 2023 Dec 11;9(1):97
Succinate signaling attenuates high-fat diet-induced metabolic disturbance and intestinal barrier dysfunction.
Li X, Huang G, Zhang Y, Ren Y, Zhang R, Zhu W, Yu K
Pharmacological research 2023 Aug;194:106865
Pharmacological research 2023 Aug;194:106865
Microbiota-derived tryptophan metabolites indole-3-lactic acid is associated with intestinal ischemia/reperfusion injury via positive regulation of YAP and Nrf2.
Zhang FL, Chen XW, Wang YF, Hu Z, Zhang WJ, Zhou BW, Ci PF, Liu KX
Journal of translational medicine 2023 Apr 18;21(1):264
Journal of translational medicine 2023 Apr 18;21(1):264
Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.
Rehman AU, Siddiqui NZ, Farooqui NA, Alam G, Gul A, Ahmad B, Asim M, Khan AI, Xin Y, Zexu W, Song Ju H, Xin W, Lei S, Wang L
Frontiers in nutrition 2022;9:984695
Frontiers in nutrition 2022;9:984695
Qingchang Wenzhong Decoction Prevents the Occurrence of Intestinal Tumors by Regulating Intestinal Microbiota and Gasdermin E.
Ren L, Zhang Z, Zhao W, Zhao B, Chen X, Wang Y, Chen Z, Ye J, Yang Y, Cao P
Frontiers in physiology 2022;13:917323
Frontiers in physiology 2022;13:917323
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
Siddiqui NZ, Rehman AU, Yousuf W, Khan AI, Farooqui NA, Zang S, Xin Y, Wang L
Gut pathogens 2022 Sep 17;14(1):39
Gut pathogens 2022 Sep 17;14(1):39
RhoB affects colitis through modulating cell signaling and intestinal microbiome.
Yang J, Pei G, Sun X, Xiao Y, Miao C, Zhou L, Wang B, Yang L, Yu M, Zhang ZS, Keller ET, Yao Z, Wang Q
Microbiome 2022 Sep 16;10(1):149
Microbiome 2022 Sep 16;10(1):149
Calpain-1: a Novel Antiviral Host Factor Identified in Porcine Small Intestinal Mucus.
Li Y, Wang X, Zhang E, Liu R, Yang C, Duan Y, Jiang Y, Yang Q
mBio 2022 Oct 26;13(5):e0035822
mBio 2022 Oct 26;13(5):e0035822
Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice.
Cai G, Wu C, Mao N, Song Z, Yu L, Zhu T, Peng S, Yang Y, Liu Z, Wang D
International journal of biological macromolecules 2022 Oct 1;218:356-367
International journal of biological macromolecules 2022 Oct 1;218:356-367
Efficacy of Probiotic Consortium Transplantation on Experimental Necrotizing Enterocolitis.
Tian B, Zhang Y, Deng C, Guo C
The Journal of surgical research 2022 Nov;279:598-610
The Journal of surgical research 2022 Nov;279:598-610
Enhanced therapeutic effect on colitis with powder formulations of Painong San associated with the promotion of intestinal adhesion and absorption.
Li J, Rui X, Xu L, Liu Y, Yang Y, Yin D
Journal of ethnopharmacology 2022 May 10;289:115030
Journal of ethnopharmacology 2022 May 10;289:115030
Effective Oral RNA Interference (RNAi) Administration to Adult Anopheles gambiae Mosquitoes.
Taracena M, Hunt C, Pennington P, Andrew D, Jacobs-Lorena M, Dotson E, Wells M
Journal of visualized experiments : JoVE 2022 Mar 1;(181)
Journal of visualized experiments : JoVE 2022 Mar 1;(181)
Protein restriction during the fetal period upregulates IL1B and IL13 while suppressing Muc2 expression in the jejunum of mice after weaning.
Adachi H, Kudo M, Ishiyama S, Mochizuki K
Nutrition (Burbank, Los Angeles County, Calif.) 2022 Jun;98:111605
Nutrition (Burbank, Los Angeles County, Calif.) 2022 Jun;98:111605
The Protective Effects of Apigenin Against Radiation-Induced Intestinal Injury.
Liu D, Peng R, Chen Z, Yu H, Wang S, Dong S, Li W, Shao W, Dai J, Li F, Jiang Q, Sun W
Dose-response : a publication of International Hormesis Society 2022 Jul-Sep;20(3):15593258221113791
Dose-response : a publication of International Hormesis Society 2022 Jul-Sep;20(3):15593258221113791
Chitosan Oligosaccharide Attenuates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction through Suppressing the Inflammatory Response and Oxidative Stress in Mice.
Tao W, Wang G, Pei X, Sun W, Wang M
Antioxidants (Basel, Switzerland) 2022 Jul 17;11(7)
Antioxidants (Basel, Switzerland) 2022 Jul 17;11(7)
Microbial hydrogen economy alleviates colitis by reprogramming colonocyte metabolism and reinforcing intestinal barrier.
Ge L, Qi J, Shao B, Ruan Z, Ren Y, Sui S, Wu X, Sun X, Liu S, Li S, Xu C, Song W
Gut microbes 2022 Jan-Dec;14(1):2013764
Gut microbes 2022 Jan-Dec;14(1):2013764
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
Wang Q, Wang C, Abdullah, Tian W, Qiu Z, Song M, Cao Y, Xiao J
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2241-2252
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2241-2252
Dietary κ-carrageenan facilitates gut microbiota-mediated intestinal inflammation.
Wu W, Zhou J, Xuan R, Chen J, Han H, Liu J, Niu T, Chen H, Wang F
Carbohydrate polymers 2022 Feb 1;277:118830
Carbohydrate polymers 2022 Feb 1;277:118830
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
Hou Z, Ding Q, Li Y, Zhao Z, Yan F, Li Y, Wang X, Xu J, Chen W, Wu G, Ruan X, Zhao L
EBioMedicine 2022 Aug;82:104181
EBioMedicine 2022 Aug;82:104181
Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.
Liu Z, Jiang Z, Zhang Z, Liu T, Fan Y, Liu T, Peng N
Microbiology spectrum 2022 Aug 31;10(4):e0064122
Microbiology spectrum 2022 Aug 31;10(4):e0064122
Diarrhoeal pathogenesis in Salmonella infection may result from an imbalance in intestinal epithelial differentiation through reduced Notch signalling.
Quach A, Jayaratne RR, Lee BJ, Ibeawuchi SR, Lim E, Das S, Barrett KE
The Journal of physiology 2022 Apr;600(8):1851-1865
The Journal of physiology 2022 Apr;600(8):1851-1865
Anemone chinensis Bunge aqueous enema alleviates dextran sulfate sodium-induced colitis via inhibition of inflammation and regulation of the colonic mucosal microbiota.
Dong L, Fan X, Li Q, Li J, Chen G, Yang D, Li Y, Zhao L, Yin H, Wang X, Liu X, Zhao Z, Lin S
Journal of ethnopharmacology 2022 Apr 24;288:114916
Journal of ethnopharmacology 2022 Apr 24;288:114916
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Qi R, Zhang Z, Wang J, Qiu X, Wang Q, Yang F, Huang J, Liu Z
Frontiers in microbiology 2021;12:623673
Frontiers in microbiology 2021;12:623673
Polydatin has anti-inflammatory and antioxidant effects in LPS-induced macrophages and improves DSS-induced mice colitis.
Chen G, Yang Z, Wen D, Guo J, Xiong Q, Li P, Zhao L, Wang J, Wu C, Dong L
Immunity, inflammation and disease 2021 Sep;9(3):959-970
Immunity, inflammation and disease 2021 Sep;9(3):959-970
Arsenic exposure induces intestinal barrier damage and consequent activation of gut-liver axis leading to inflammation and pyroptosis of liver in ducks.
Zhong G, Wan F, Lan J, Jiang X, Wu S, Pan J, Tang Z, Hu L
The Science of the total environment 2021 Sep 20;788:147780
The Science of the total environment 2021 Sep 20;788:147780
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Hu S, Li S, Liu Y, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Liao M, Zhang Y, Qiu Y, Wu Z, Zhong Z, Zeng X, Zeng Y, Xiong L, Wen Y, Liu R
Food & function 2021 Oct 19;12(20):9844-9854
Food & function 2021 Oct 19;12(20):9844-9854
Shaoyao decoction attenuates DSS-induced ulcerative colitis, macrophage and NLRP3 inflammasome activation through the MKP1/NF-κB pathway.
Wei YY, Fan YM, Ga Y, Zhang YN, Han JC, Hao ZH
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov;92:153743
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov;92:153743
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
Hu S, Chen Y, Zhao S, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
Clostridium tyrobutyricum Protects against LPS-Induced Colonic Inflammation via IL-22 Signaling in Mice.
Xiao Z, Liu L, Jin Y, Pei X, Sun W, Wang M
Nutrients 2021 Jan 13;13(1)
Nutrients 2021 Jan 13;13(1)
λ-carrageenan exacerbates Citrobacter rodentium-induced infectious colitis in mice by targeting gut microbiota and intestinal barrier integrity.
Wu W, Zhou D, Xuan R, Zhou J, Liu J, Chen J, Han H, Niu T, Li X, Chen H, Wang F
Pharmacological research 2021 Dec;174:105940
Pharmacological research 2021 Dec;174:105940
Alhagi honey polysaccharides attenuate intestinal injury and immune suppression in cyclophosphamide-induced mice.
Cai G, Wu Y, Wusiman A, Gu P, Mao N, Xu S, Zhu T, Feng Z, Liu Z, Wang D
Food & function 2021 Aug 2;12(15):6863-6877
Food & function 2021 Aug 2;12(15):6863-6877
Diverse cellular morphologies during lumen maturation in Anopheles gambiae larval salivary glands.
Chiu M, Trigg B, Taracena M, Wells M
Insect molecular biology 2021 Apr;30(2):210-230
Insect molecular biology 2021 Apr;30(2):210-230
Teasaponin Ameliorates Murine Colitis by Regulating Gut Microbiota and Suppressing the Immune System Response.
Yang H, Cai R, Kong Z, Chen Y, Cheng C, Qi S, Gu B
Frontiers in medicine 2020;7:584369
Frontiers in medicine 2020;7:584369
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
Bai R, Sun D, Chen M, Shi X, Luo L, Yao Z, Liu Y, Ge X, Gao X, Hu GF, Zhou W, Sheng J, Xu Z
The EMBO journal 2020 Jul 1;39(13):e103325
The EMBO journal 2020 Jul 1;39(13):e103325
Interleukin-10 expands transit-amplifying cells while depleting Lgr5(+) stem cells via inhibition of Wnt and notch signaling.
Deng F, Hu J, Yang X, Wang Y, Lin Z, Sun Q, Liu K
Biochemical and biophysical research communications 2020 Dec 17;533(4):1330-1337
Biochemical and biophysical research communications 2020 Dec 17;533(4):1330-1337
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Gao J, Li Y, Wan Y, Hu T, Liu L, Yang S, Gong Z, Zeng Q, Wei Y, Yang W, Zeng Z, He X, Huang SH, Cao H
Frontiers in microbiology 2019;10:477
Frontiers in microbiology 2019;10:477
SRC-3 protects intestine from DSS-induced colitis by inhibiting inflammation and promoting goblet cell differentiation through enhancement of KLF4 expression.
Chen W, Zhuo M, Lu X, Xia X, Zhao Y, Huang Z, Xu J, Li W, Yu C
International journal of biological sciences 2018;14(14):2051-2064
International journal of biological sciences 2018;14(14):2051-2064
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