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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA023739 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA023739, RRID:AB_1854308
- Product name
- Anti-NAPRT
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human NAPRT, Gene description: nicotinate phosphoribosyltransferase, Alternative Gene Names: NAPRT1, PP3856, Validated applications: ICC, IHC, WB, Uniprot ID: Q6XQN6, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Nicotinaldehyde, a Novel Precursor of NAD Biosynthesis, Abrogates the Anti-Cancer Activity of an NAD-Lowering Agent in Leukemia
Poly(ADP-ribose) Glycohydrolase Inhibition Sequesters NAD+ to Potentiate the Metabolic Lethality of Alkylating Chemotherapy in IDH-Mutant Tumor Cells
Novel NAPRT specific antibody identifies small cell lung cancer and neuronal cancers as promising clinical indications for a NAMPT inhibitor/niacin co-administration strategy
Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors
Mapping the Subcellular Protein Distribution in Three Human Cell Lines
Matsumoto S, Biniecka P, Bellotti A, Duchosal M, Nahimana A
Cancers 2023;15(3):787
Cancers 2023;15(3):787
Poly(ADP-ribose) Glycohydrolase Inhibition Sequesters NAD+ to Potentiate the Metabolic Lethality of Alkylating Chemotherapy in IDH-Mutant Tumor Cells
Nagashima H, Lee C, Tateishi K, Higuchi F, Subramanian M, Rafferty S, Melamed L, Miller J, Wakimoto H, Cahill D
Cancer Discovery 2020;10(11):1672-1689
Cancer Discovery 2020;10(11):1672-1689
Novel NAPRT specific antibody identifies small cell lung cancer and neuronal cancers as promising clinical indications for a NAMPT inhibitor/niacin co-administration strategy
Cole J, Guiot M, Gravel M, Bernier C, Shore G, Roulston A
Oncotarget 2017;8(44):77846-77859
Oncotarget 2017;8(44):77846-77859
Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors
Duarte-Pereira S, Pereira-Castro I, Silva S, Correia M, Neto C, da Costa L, Amorim A, Silva R
Oncotarget 2015;7(2):1973-1983
Oncotarget 2015;7(2):1973-1983
Mapping the Subcellular Protein Distribution in Three Human Cell Lines
Fagerberg L, Stadler C, Skogs M, Hjelmare M, Jonasson K, Wiking M, Åbergh A, Uhlén M, Lundberg E
Journal of Proteome Research 2011;10(8):3766-3777
Journal of Proteome Research 2011;10(8):3766-3777
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human small intestine and skeletal muscle tissues using HPA023739 antibody. Corresponding NAPRT RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
