Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- MAB3877 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB3877, RRID:AB_10678197
- Product name
- TNFRSF21 monoclonal antibody, clone DR-6-04-EC
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against partial recombinant TNFRSF21.
- Isotype
- IgG
- Antibody clone number
- DR-6-04-EC
- Storage
- Store at 4°C. Do not freeze.Aliquot to avoid repeated freezing and thawing.
Submitted references Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6.
Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB.
Identification and functional characterization of DR6, a novel death domain-containing TNF receptor.
Schmidt CS, Liu J, Zhang T, Song HY, Sandusky G, Mintze K, Benschop RJ, Glasebrook A, Yang DD, Na S
The Journal of experimental medicine 2003 Jan 6;197(1):51-62
The Journal of experimental medicine 2003 Jan 6;197(1):51-62
Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB.
Kasof GM, Lu JJ, Liu D, Speer B, Mongan KN, Gomes BC, Lorenzi MV
Oncogene 2001 Nov 29;20(55):7965-75
Oncogene 2001 Nov 29;20(55):7965-75
Identification and functional characterization of DR6, a novel death domain-containing TNF receptor.
Pan G, Bauer JH, Haridas V, Wang S, Liu D, Yu G, Vincenz C, Aggarwal BB, Ni J, Dixit VM
FEBS letters 1998 Jul 24;431(3):351-6
FEBS letters 1998 Jul 24;431(3):351-6
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Detection of TNFRSF21 transiently transfected into HeLa cells (green) using TNFRSF21 monoclonal antibody, clone DR-6-04-EC (Cat # MAB3877). Cell nuclei visualized by DAPI (blue).
- Validation comment
- Immunofluorescence
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Flow cytometry analysis of cell surface expression of TNFRSF21 in 6 different cell lines using TNFRSF21 monoclonal antibody, clone DR-6-04-EC (Cat # MAB3877) (detection by Goat anti-mouse IgG1 PE).
- Validation comment
- Flow Cytometry