ALX-210-569-C100

antibody from Enzo Life Sciences

Targeting: TNFRSF21 CD358, DR6

Western blot (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ALX-210-569-C100

Provider

Enzo Life Sciences

Proper citation

Enzo Life Sciences Cat#ALX-210-569-C100, RRID:AB_2051331

Product name

DR6 (human) polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant protein fragment

Reactivity

Human

Host

Rabbit

Vial size

100 μg

Storage

-20°C

Handling

Avoid freeze/thaw cycles.

References

Submitted references

T-cell activation triggers death receptor-6 expression in a NF-κB and NF-AT dependent manner.

Klíma M, Broučková A, Koc M, Anděra L
Molecular immunology 2011 Jul;48(12-13):1439-47

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Functional analysis of the posttranslational modifications of the death receptor 6.

Klíma M, Zájedová J, Doubravská L, Andera L
Biochimica et biophysica acta 2009 Oct;1793(10):1579-87

Immunocytochemistry

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Immunodetection of transfected human DR6 in HEK 293 cells using PAb to DR6 (human) (Prod. No. ALX-210-569). Asteriks represent N-glycosylated forms and arrow shows unglycosylated form of DR6.

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Immunocytochemical analysis of transfected human DR6 in HEK 293 cells using PAb to DR6 (human) (Prod. No. ALX-210-569). Confocal microscopy shows membrane localization of DR6; nuclei stained with DRAQ5 (Prod. No. BOS-889-001).

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Immunodetection of endogenous human DR6 in hematopoietic cells using PAb to DR6 (human) (Prod. No. ALX-210-569). Arrow represents unglycosylated form and asteriks shows alternatively translated form of DR6.