PLPPR1

This gene encodes a member of the plasticity-related gene (PRG) family. Members of the PRG family mediate lipid phosphate phosphatase activity in neurons and are known to be involved in neuronal plasticity. The protein encoded by this gene does not perform its function through enzymatic phospholipid degradation. This gene is strongly expressed in brain. It shows dynamic expression regulation during brain development and neuronal excitation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

Description

Phospholipid phosphatase related 1

Tissue specificity

Tissue enhanced (brain, choroid plexus, kidney)

Subcell location

Nucleoplasm

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Kim et al 2014)

Chromosome

9 (101028727 - 101325135)

Ensembl ID

ENSG00000148123  (ver. 103.38)

Orthologs

Mouse Plppr1: ENSMUSG00000063446

UniProt

Q8TBJ4

neXtProt

NX_Q8TBJ4

Human splice variants
Mouse splice variants

Protein structure