HPGDS

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. [provided by RefSeq, Jul 2008]

Description

hematopoietic prostaglandin D synthase

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

4:q22.3 (94298535 - 94342876)

Ensembl ID

ENSG00000163106  (ver. 98.38)

Orthologs

Mouse Hpgds: ENSMUSG00000029919

UniProt

O60760

neXtProt

NX_O60760

Human splice variants
Mouse splice variants