Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL1917 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-IL12RB1 monoclonal Antibody, clone 225 [PE]
- Antibody type
- Monoclonal
- Description
- The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
- Reactivity
- Mouse
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Antibody clone number
- 225
- Storage
- -20°C, Avoid freeze / thaw cycles
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