ABIN319776

antibody from antibodies-online

Targeting: ITGAV CD51, MSK8, VNRA, VTNR

Immunoprecipitation (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN319776

Provider

antibodies-online

Product name

anti-Integrin alpha V (ITGAV) antibody

Antibody type

Monoclonal

Antigen

Osteoclasts from osteoclastomas. Spleen cells from immunised mice were fused with cells of the mouse X63.Ag8.653 myeloma cell line.

Description

Affinity Chromatography on Protein A.

Reactivity

Human, Chicken/Avian

Host

Mouse

Isotype

IgG

Antibody clone number

23C6

Vial size

25 μg

Concentration

1.0 mg/mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

The osteoclast functional antigen, implicated in the regulation of bone resorption, is biochemically related to the vitronectin receptor.

Davies J, Warwick J, Totty N, Philp R, Helfrich M, Horton M
The Journal of cell biology 1989 Oct;109(4 Pt 1):1817-26

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Expression of the vitronectin receptor during embryonic development; an immunohistological study of the ontogeny of the osteoclast in the rabbit.

Simpson A, Horton MA
British journal of experimental pathology 1989 Jun;70(3):257-65

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Monoclonal antibodies to osteoclastomas (giant cell bone tumors): definition of osteoclast-specific cellular antigens.

Horton MA, Lewis D, McNulty K, Pringle JA, Chambers TJ
Cancer research 1985 Nov;45(11 Pt 2):5663-9