ITGAV

gene product
CD51, MSK8, VNRA, VTNR
This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. Note that the integrin alpha 5 and integrin alpha V chains are produced by distinct genes. [provided by RefSeq, Jan 2015]
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Antibodies

 

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Antibodypedia Validation Initiative

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Conjugate

  or   Clear
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1205 antibodies from 41 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
12 antibodies
R&D Systems
39 antibodies
Novus Biologicals
121 antibodies
antibodies-online
387 antibodies
Enzo Life Sciences
2 antibodies
Boster Biological Technology
3 antibodies
OriGene
24 antibodies
NSJ Bioreagents
1 antibody
Biorbyt
55 antibodies
Invitrogen Antibodies
10 antibodies
BioLegend
16 antibodies
Acris Antibodies GmbH
20 antibodies
LifeSpan BioSciences, Inc.
167 antibodies