327903

antibody from BioLegend
Targeting: ITGAV CD51, MSK8, VNRA, VTNR
Provider product page for 327903
ELISA
Immunoprecipitation
Flow cytometry
Blocking/Neutralizing

Antibody data

Product number
327903 - Provider product page
Provider
BioLegend
Product name
LEAF™ Purified anti-human CD51 [NKI-M9]
Antibody type
Monoclonal
Antigen
Melonama cells
Description
CD51 is a type I integral membrane glycoprotein, known as vitronectin receptor α chain, or integrin αV. It forms heterodimer with integrin β1 (CD29), β3 (CD61), β5, β6, or β8. CD51 contains two disulfide-linked subunits of 125 kD and 24 kD, and is expressed on endothelial cells, fibroblasts, macrophages, platelets, osteoclasts, neuroblastoma, melanoma, and hepatoma cells. Many extracellular matrix proteins with RGD-motifs are CD51 ligands. In association with its β chains, CD51 binds vitronectin, von Willebrand factor, fibronectin, thrombospondin, osteopontin, fibrinogen, and laminin. CD51, as an adhesion molecule, plays important roles in leukocytes homing and rolling, mediates bone absorption and angiogenesis.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
50 µg
Concentration
1 mg/ml
Storage
The antibody solution should be stored undiluted at 4 °C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
ITGAV protein structure - 327903 shown in red.