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- Antibody Data
- Antigen structure
- References [16]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10754-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10754-2-AP, RRID:AB_2174610
- Product name
- PTGDS antibody
- Antibody type
- Polyclonal
- Description
- PTGDS antibody (Cat. #10754-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Revealing the biochemical regulations of L-PGDS in hepatic insulin-resistance using HepG2 cells.
FADS1 contributes to anesthesia/surgery-induced cognitive impairment by aggravating omega-6 fatty acid metabolic disruption in aged mice.
Integrative Machine Learning Analysis of Programmed Cell Death Pathways Identifies Novel Diagnostic Biomarkers for Atrial Fibrillation.
Targeting PTGDS inhibits pro-inflammatory fibroblasts associated with skin fibrosis in systemic sclerosis.
Prioritization of potential drug targets for diabetic kidney disease using integrative omics data mining and causal inference.
Identification and experimental verification of immune-related hub genes in intervertebral disc degeneration.
The tertiary lymphoid structure-related signature identified PTGDS in regulating PD-L1 and promoting the proliferation and migration of glioblastoma.
Exploring diverse programmed cell-death patterns to develop a novel gene signature for predicting the prognosis of lung adenocarcinoma patients.
Transcriptomic analysis reveals potential crosstalk genes and immune relationship between triple-negative breast cancer and depression.
MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson's disease.
Zileuton, a 5-Lipoxygenase Inhibitor, Attenuates Haemolysate-Induced BV-2 Cell Activation by Suppressing the MyD88/NF-κB Pathway.
Comparative Proteomics and Phosphoproteomics Analysis Reveal the Possible Breed Difference in Yorkshire and Duroc Boar Spermatozoa.
MicroRNA-138 improves LPS-induced trophoblast dysfunction through targeting RELA and NF-κB signaling.
Decreased PTGDS Expression Predicting Poor Survival of Endometrial Cancer by Integrating Weighted Gene Co-Expression Network Analysis and Immunohistochemical Validation.
Proteome analysis of human cerebrospinal fluid as a diagnostic biomarker in patients with meningioma.
Proteome analysis of human cerebrospinal fluid as a diagnostic biomarker in patients with meningioma.
Khairnar R, Islam MA, Singh K, Shetty DK, Yadav A, Dukhande VV, Kumar S
Prostaglandins & other lipid mediators 2026 Jan;182:107052
Prostaglandins & other lipid mediators 2026 Jan;182:107052
FADS1 contributes to anesthesia/surgery-induced cognitive impairment by aggravating omega-6 fatty acid metabolic disruption in aged mice.
Chen Z, Wu Q, Ma J, Shi Y, Zhang Q, Wu H, Zhang Y, Li Z, Ruan X, Xiong L, Cong P, Tian L
Journal of neuroinflammation 2026 Feb 11;23(1)
Journal of neuroinflammation 2026 Feb 11;23(1)
Integrative Machine Learning Analysis of Programmed Cell Death Pathways Identifies Novel Diagnostic Biomarkers for Atrial Fibrillation.
Peng H, Xia Z, Zhao Y, Xie D
Journal of inflammation research 2025;18:18247-18266
Journal of inflammation research 2025;18:18247-18266
Targeting PTGDS inhibits pro-inflammatory fibroblasts associated with skin fibrosis in systemic sclerosis.
Fang D, Yuan X, Yi J, Li Z, Li X, Guo W, Wang J, Mu R
Rheumatology (Oxford, England) 2025 Oct 1;64(10):5551-5561
Rheumatology (Oxford, England) 2025 Oct 1;64(10):5551-5561
Prioritization of potential drug targets for diabetic kidney disease using integrative omics data mining and causal inference.
Zhang J, Peng J, Yu C, Ning Y, Lin W, Ni M, Xie Q, Yang C, Liang H, Lin M
Journal of pharmaceutical analysis 2025 Aug;15(8):101265
Journal of pharmaceutical analysis 2025 Aug;15(8):101265
Identification and experimental verification of immune-related hub genes in intervertebral disc degeneration.
Huang Z, Cai X, Shen X, Chen Z, Zhang Q, Liu Y, Lu B, Xu B, Li Y
Heliyon 2024 Jul 30;10(14):e34530
Heliyon 2024 Jul 30;10(14):e34530
The tertiary lymphoid structure-related signature identified PTGDS in regulating PD-L1 and promoting the proliferation and migration of glioblastoma.
Wu W, Li H, Wang Z, Dai Z, Liang X, Luo P, Liu K, Zhang H, Zhang N, Li S, Zhang C
Heliyon 2024 Jan 15;10(1):e23915
Heliyon 2024 Jan 15;10(1):e23915
Exploring diverse programmed cell-death patterns to develop a novel gene signature for predicting the prognosis of lung adenocarcinoma patients.
Ma Z, Wang Y, Yu Y, Fu F, Zhang Y
Journal of thoracic disease 2024 Feb 29;16(2):911-923
Journal of thoracic disease 2024 Feb 29;16(2):911-923
Transcriptomic analysis reveals potential crosstalk genes and immune relationship between triple-negative breast cancer and depression.
Zhuo Z, Lu W, Zhang L, Zhang D, Cui Y, Wu X, Mei H, Chang L, Song Q
Discover oncology 2024 Dec 18;15(1):762
Discover oncology 2024 Dec 18;15(1):762
MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson's disease.
Geng L, Gao W, Saiyin H, Li Y, Zeng Y, Zhang Z, Li X, Liu Z, Gao Q, An P, Jiang N, Yu X, Chen X, Li S, Chen L, Lu B, Li A, Chen G, Shen Y, Zhang H, Tian M, Zhang Z, Li J
Molecular neurodegeneration 2023 Dec 1;18(1):94
Molecular neurodegeneration 2023 Dec 1;18(1):94
Zileuton, a 5-Lipoxygenase Inhibitor, Attenuates Haemolysate-Induced BV-2 Cell Activation by Suppressing the MyD88/NF-κB Pathway.
Su HY, Tsai YC, Tsai HP, Lin CL
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
Comparative Proteomics and Phosphoproteomics Analysis Reveal the Possible Breed Difference in Yorkshire and Duroc Boar Spermatozoa.
Xu Y, Han Q, Ma C, Wang Y, Zhang P, Li C, Cheng X, Xu H
Frontiers in cell and developmental biology 2021;9:652809
Frontiers in cell and developmental biology 2021;9:652809
MicroRNA-138 improves LPS-induced trophoblast dysfunction through targeting RELA and NF-κB signaling.
Yin A, Chen Q, Zhong M, Jia B
Cell cycle (Georgetown, Tex.) 2021 Mar-Mar;20(5-6):508-521
Cell cycle (Georgetown, Tex.) 2021 Mar-Mar;20(5-6):508-521
Decreased PTGDS Expression Predicting Poor Survival of Endometrial Cancer by Integrating Weighted Gene Co-Expression Network Analysis and Immunohistochemical Validation.
Zou R, Zheng M, Tan M, Xu H, Luan N, Zhu L
Cancer management and research 2020;12:5057-5075
Cancer management and research 2020;12:5057-5075
Proteome analysis of human cerebrospinal fluid as a diagnostic biomarker in patients with meningioma.
Kim JH, Lee SK, Yoo YC, Park NH, Park DB, Yoo JS, An HJ, Park YM, Cho KG
Medical science monitor : international medical journal of experimental and clinical research 2012 Nov;18(11):BR450-60
Medical science monitor : international medical journal of experimental and clinical research 2012 Nov;18(11):BR450-60
Proteome analysis of human cerebrospinal fluid as a diagnostic biomarker in patients with meningioma.
Kim JH, Lee SK, Yoo YC, Park NH, Park DB, Yoo JS, An HJ, Park YM, Cho KG
Medical science monitor : international medical journal of experimental and clinical research 2012 Nov;18(11):BR450-60
Medical science monitor : international medical journal of experimental and clinical research 2012 Nov;18(11):BR450-60
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10754-2-AP(PGDS antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PTGDS antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PTGDS. This antibody recognizes human antigen. The PTGDS antibody has been validated for the following applications: ELISA, WB, IHC analysis.
