Tissue expression
Cell line expression
Protein structure
PTGDS
Prostaglandin D2 synthaseL-PGDS, PGDS
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 10754-2-AP | 1 references | Polyclonal |
WB
EL
IHC
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Novus Biologicals | NBP1-79280 | 2 references | Polyclonal |
WB
IHC |
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LSBio | LS-C450784 | Polyclonal |
WB
IHC |
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antibodies-online | ABIN502983 | 1 references | Polyclonal |
WB
IHC |
|
NovoPro Bioscience Inc. | 114266 | Polyclonal |
WB
EL
IHC
|
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