634902

antibody from BioLegend

Targeting: MMP3 STMY, STMY1

ELISA

Immunohistochemistry

Antibody data

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Validation data

Product number: 634902 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#634902, RRID:AB_2146594
Product name: Purified anti-MMP3
Antibody type: Monoclonal
Antigen: Ovalbumin-conjugated synthetic peptide CKSLRKLEPELH
Description: Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP1 cleaves collagens of types I, II, III, VII and X.MMP1 is thought to play an important role in rheumatoid and osteo-arthritis pathogenesis as mediators of cartilage and bone destruction. Clone F15P3B6 has been shown to be useful for western blotting and immunohistochemistry of human MMP1.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: Upon receipt, store undiluted at 4°C.

MMP3 protein structure - 634902 shown in red.