Tissue expression
Cell line expression
Protein structure
MMP3
Matrix metallopeptidase 3STMY, STMY1
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | 701285 | Monoclonal |
WB
EL
ICC
IHC
FC
OA |
||
Proteintech Group | 17873-1-AP | 88 references | Polyclonal |
WB
EL
ICC
IHC |
|
R&D Systems | MAB513 | 4 references | Monoclonal |
WB
ICC
IHC
FC |
|
Novus Biologicals | MAB513 | 4 references | Monoclonal |
WB
ICC
IHC
FC |
|
antibodies-online | ABIN969539 | 2 references | Monoclonal |
WB
EL
FC
|
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