Tissue expression
Cell line expression
ADGRG1
gene productGPR56, TM7LN4, TM7XN1
This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
- Description
- Adhesion G protein-coupled receptor G1
- Tissue specificity
- Tissue enhanced (thyroid gland)
- Predicted location
- Intracellular, Membrane, Secreted to blood
- Protein family
- Disease related genes
G-protein coupled receptors
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
- Chromosome
- 16:q21 (57610652 - 57665580)
- Ensembl ID
- ENSG00000205336 (ver. 103.38)
- Orthologs
- Mouse Adgrg1: ENSMUSG00000031785
- UniProt
- Q9Y653
- neXtProt
- NX_Q9Y653
Human splice variants
Mouse splice variants
Ensembl | UniProt | RefSeq | Entrez |
---|---|---|---|
ENSMUST00000093271 ENSMUSP00000090959 |
Q8K209.151 Q8K209 | NP_061370.2 NP_061370 | Adgrg1 14766 |
ENSMUST00000179619 ENSMUSP00000137520 |
Q8K209.151 Q8K209 | NP_001185823.1 NP_001185823 | Adgrg1 14766 |
ENSMUST00000211944 ENSMUSP00000148386 |
Adgrg1 14766 | ||
ENSMUST00000211984 ENSMUSP00000148412 |
Adgrg1 14766 | ||
ENSMUST00000212118 ENSMUSP00000148304 |
Adgrg1 14766 | ||
ENSMUST00000212141 ENSMUSP00000148331 |
Adgrg1 14766 | ||
ENSMUST00000212531 ENSMUSP00000148650 |
Adgrg1 14766 | ||
ENSMUST00000212581 ENSMUSP00000148742 |
Adgrg1 14766 | ||
ENSMUST00000212660 ENSMUSP00000148644 |
Q8K209.151 Q8K209 | Adgrg1 14766 | |
ENSMUST00000212799 ENSMUSP00000148349 |
Adgrg1 14766 | ||
ENSMUST00000212956 ENSMUSP00000148374 |
Adgrg1 14766 | ||
ENSMUST00000212976 ENSMUSP00000148439 |
Adgrg1 14766 | ||
ENSMUST00000212995 ENSMUSP00000148309 |
Adgrg1 14766 |
* nTPM: Normalized TPM levels represent consensus gene expression calculated using two data sets. Read more
RNA data sourced from Human Protein Atlas.
Featured antibodies
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0 references | Polyclonal |
WB
EL ICC
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