Tissue expression
Cell line expression

CHRNB4

gene product
 
This gene is found within a conserved gene cluster and encodes one of the beta subunits of the nicotinic acetylcholine receptor (nAChRs) superfamily which form ligand-gated ion channels with a central pore that forms a cation channel. Neuronal nAChRs are pentameric structures that can be either homomeric or heteromeric, with heteromeric structures containing both alpha and beta subunits. Each subunit contains an extracellular amino terminus and four transmembrane domains. Nicotine is one of the agonists that binds to the receptor. Variants in this gene have been associated with nicotine dependence and lung cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2017]
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Antibodies

 

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Supportive data in Antibodypedia
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173 antibodies from 28 providers.

Antibody properties

Applications

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
50 antibodies
Invitrogen Antibodies
7 antibodies
Proteintech Group
1 antibody
Novus Biologicals
4 antibodies
NovoPro Bioscience Inc.
3 antibodies
LifeSpan BioSciences, Inc.
39 antibodies
Affinity Biosciences
1 antibody
OriGene
1 antibody
GeneTex
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Antibodies.com
1 antibody
Boster Biological Technology
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
Biorbyt
8 antibodies
Abnova Corporation
2 antibodies
Acris Antibodies GmbH
3 antibodies
Abgent
3 antibodies
Aviva Systems Biology
2 antibodies
Creative Diagnostics
3 antibodies
MyBioSource
3 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
25 antibodies
Leading Biology
3 antibodies
Abbexa
2 antibodies
ProSci
2 antibodies
Everest Biotech
1 antibody
GenWay
2 antibodies
Creative Biolabs
1 antibody