ABIN1882125
antibody from antibodies-online
Targeting: UPF1
HUPF1, KIAA0221, NORF1, pNORF1, RENT1, smg-2
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN1882125 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-UPF1 Regulator of Nonsense Transcripts Homolog (Yeast) (UPF1) (N-Term), (Glu22), (AA 7-37) antibody
- Antibody type
- Polyclonal
- Antigen
- This RENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-37 amino acids from the N-terminal region of human RENT1.
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term,Glu22,AA 7-37
- Antibody clone number
- RB8018
- Vial size
- 400 μL
- Concentration
- 2 mg/mL
Submitted references Two molecular pathways (NMD and ERAD) contribute to a genetic epilepsy associated with the GABA(A) receptor GABRA1 PTC mutation, 975delC, S326fs328X.
Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts.
Identification of delta helicase as the bovine homolog of HUPF1: demonstration of an interaction with the third subunit of DNA polymerase delta.
Kang JQ, Shen W, Macdonald RL
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Mar 4;29(9):2833-44
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Mar 4;29(9):2833-44
Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts.
Mendell JT, ap Rhys CM, Dietz HC
Science (New York, N.Y.) 2002 Oct 11;298(5592):419-22
Science (New York, N.Y.) 2002 Oct 11;298(5592):419-22
Identification of delta helicase as the bovine homolog of HUPF1: demonstration of an interaction with the third subunit of DNA polymerase delta.
Carastro LM, Tan CK, Selg M, Jack HM, So AG, Downey KM
Nucleic acids research 2002 May 15;30(10):2232-43
Nucleic acids research 2002 May 15;30(10):2232-43
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of RENT1 (arrow) using rabbit polyclonal RENT1 Antibody (N-term E22) (ABIN1882125) . 293 cell lysates (2 μg/lane) either nontransfected (Lane 1) or transiently transfected with the RENT1 gene (Lane 2) (Origene Technologies).