23379-1-AP
antibody from Proteintech Group
		Targeting: UPF1
		
		HUPF1, KIAA0221, NORF1, pNORF1, RENT1, smg-2	
	
	
	
	
Antibody data
- Antibody Data
 - Antigen structure
 - References [10]
 - Comments [0]
 - Validations
 - Western blot [1]
 - Immunocytochemistry [1]
 
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Validation data
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- Product number
 - 23379-1-AP - Provider product page

 - Provider
 - Proteintech Group
 - Proper citation
 - Proteintech Cat#23379-1-AP, RRID:AB_11232421
 - Product name
 - UPF1 antibody
 - Antibody type
 - Polyclonal
 - Description
 - UPF1 antibody (Cat. #23379-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
 - Reactivity
 - Human
 - Host
 - Rabbit
 - Conjugate
 - Unconjugated
 - Isotype
 - IgG
 - Vial size
 - 20ul, 150ul
 
Submitted references		Nonsense-mediated mRNA decay promote C2C12 cell proliferation by targeting PIK3R5.
				
The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation.
				
RAPIDASH: A tag-free enrichment of ribosome-associated proteins reveals compositional dynamics in embryonic tissues and stimulated macrophages.
				
Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1.
				
Hyperglycemia Enhances Immunosuppression and Aerobic Glycolysis of Pancreatic Cancer Through Upregulating Bmi1-UPF1-HK2 Pathway.
				
The biological behavior of tRNA-derived fragment tRF-Leu-AAG in pancreatic cancer cells.
				
UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction.
				
Long noncoding RNA PVT1 promotes breast cancer proliferation and metastasis by binding miR-128-3p and UPF1.
				
PABPC1-induced stabilization of BDNF-AS inhibits malignant progression of glioblastoma cells through STAU1-mediated decay.
				
PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α.
				
		
	
			Huang Z, Peng Y, Wei Y, Tan Y
Journal of muscle research and cell motility 2023 Mar;44(1):11-23
		Journal of muscle research and cell motility 2023 Mar;44(1):11-23
The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation.
			Curdy N, Lanvin O, Cerapio JP, Pont F, Tosolini M, Sarot E, Valle C, Saint-Laurent N, Lhuillier E, Laurent C, Fournié JJ, Franchini DM
Cell reports 2023 Mar 28;42(3):112211
		Cell reports 2023 Mar 28;42(3):112211
RAPIDASH: A tag-free enrichment of ribosome-associated proteins reveals compositional dynamics in embryonic tissues and stimulated macrophages.
			Susanto TT, Hung V, Levine AG, Kerr CH, Yoo Y, Chen Y, Oses-Prieto JA, Fromm L, Fujii K, Wernig M, Burlingame AL, Ruggero D, Barna M
bioRxiv : the preprint server for biology 2023 Dec 7;
		bioRxiv : the preprint server for biology 2023 Dec 7;
Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1.
			Tong L, Rao J, Yang C, Xu J, Lu Y, Zhang Y, Cang X, Xie S, Mao J, Jiang P
iScience 2023 Aug 18;26(8):107446
		iScience 2023 Aug 18;26(8):107446
Hyperglycemia Enhances Immunosuppression and Aerobic Glycolysis of Pancreatic Cancer Through Upregulating Bmi1-UPF1-HK2 Pathway.
			Wu S, Zhang H, Gao C, Chen J, Li H, Meng Z, Bai J, Shen Q, Wu H, Yin T
Cellular and molecular gastroenterology and hepatology 2022;14(5):1146-1165
		Cellular and molecular gastroenterology and hepatology 2022;14(5):1146-1165
The biological behavior of tRNA-derived fragment tRF-Leu-AAG in pancreatic cancer cells.
			Sui S, Wang Z, Cui X, Jin L, Zhu C
Bioengineered 2022 Apr;13(4):10617-10628
		Bioengineered 2022 Apr;13(4):10617-10628
UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction.
			Zaepfel BL, Zhang Z, Maulding K, Coyne AN, Cheng W, Hayes LR, Lloyd TE, Sun S, Rothstein JD
Cell reports 2021 Mar 30;34(13):108925
		Cell reports 2021 Mar 30;34(13):108925
Long noncoding RNA PVT1 promotes breast cancer proliferation and metastasis by binding miR-128-3p and UPF1.
			Liu S, Chen W, Hu H, Zhang T, Wu T, Li X, Li Y, Kong Q, Lu H, Lu Z
Breast cancer research : BCR 2021 Dec 18;23(1):115
		Breast cancer research : BCR 2021 Dec 18;23(1):115
PABPC1-induced stabilization of BDNF-AS inhibits malignant progression of glioblastoma cells through STAU1-mediated decay.
			Su R, Ma J, Zheng J, Liu X, Liu Y, Ruan X, Shen S, Yang C, Wang D, Cai H, Li Z, Xue Y
Cell death & disease 2020 Feb 3;11(2):81
		Cell death & disease 2020 Feb 3;11(2):81
PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α.
			Hou P, Chen F, Yong H, Lin T, Li J, Pan Y, Jiang T, Li M, Chen Y, Song J, Zheng J, Bai J
Journal of experimental & clinical cancer research : CR 2019 Jul 10;38(1):301
		Journal of experimental & clinical cancer research : CR 2019 Jul 10;38(1):301
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					Supportive validation
					
									
				
				- Submitted by
 - Proteintech Group (provider)
 - Main image
 
- Experimental details
 - HepG2 cells were subjected to SDS PAGE followed by western blot with 23379-1-AP(UPF1 antibody) at dilution of 1:1000
 - Sample type
 - cell line
 
							
					Supportive validation
					
									
				
		
		- Submitted by
 - Proteintech Group (provider)
 - Main image
 
- Experimental details
 - The UPF1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human UPF1. This antibody recognizes human,mouse,rat antigen. The UPF1 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.