NBP2-48475-0.1mg

antibody from Novus Biologicals
Targeting: NDRG1 CAP43, DRG1, NDR1, RTP, TDD5
Provider product page for NBP2-48475-0.1mg
Western blot
Immunocytochemistry
Flow cytometry

Antibody data

Product number
NBP2-48475-0.1mg - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal NDRG1 Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. It recognizes a protein of 43kDa, which is identified as N-myc downstream-regulated gene 1 protein (NDRG1). The NDRG) family is comprised of four members, NDRG1, NDRG2, NDRG3 and NDRG4, which share 57-65% homology. The NDRG1 gene is ubiquitously expressed, but it is expressed most prominently in placental membranes and prostate, kidney, small intestine and ovary tissue. NDRG1 is a direct transcriptional target gene of p53 to mediated cell death and apoptosis. NDRG1 gene expression is induced by several compounds, including nickel, and produces a protein involved in stress responses, hormone responses, cell growth and differentiation. The reduced expression of NDRG1 has been found to be associated with tumor metastasis in a variety of tumors, including cancers of the breast, colon, prostate, oral cavity and oropharynx. Reportedly, overexpression of NDRG1 in hepatocellular carcinoma is an indicator of tumor aggressiveness.
Reactivity
Human
Host
Mouse
Isotype
IgG
Vial size
0.1 mg
Concentration
0.2 mg/ml
Storage
Store at 4C.
NDRG1 protein structure - NBP2-48475-0.1mg shown in red.