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Protein structure
NDRG1
N-myc downstream regulated 1CAP43, DRG1, NDR1, RTP, TDD5
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Top validated antibodies |
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| Proteintech Group |  26902-1-AP |
16 references | Polyclonal |
WB
EL
ICC
IHC
FC
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| antibodies-online | ABIN393210 |
4 references | Monoclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | H00010397-M03 |
4 references | Monoclonal |
WB
EL
ICC
IHC
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| LSBio | LS-C818174 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
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| Abnova Corporation | H00010397-M03 |
2 references | Monoclonal |
EL
ICC
IHC
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