200-301-MX7

antibody from Rockland Immunochemicals, Inc.
Targeting: FCGRT alpha-chain, FCRN
Provider product page for 200-301-MX7
Immunocytochemistry
Flow cytometry

Antibody data

Product number
200-301-MX7 - Provider product page
Provider
Rockland Immunochemicals, Inc.
Product name
Anti-hFcRn (MOUSE) Monoclonal Antibody - 200-301-MX7
Antibody type
Monoclonal
Description
The MHC class I-like Fc receptor (FcRn) functions as an intracellular trafficking receptor, uniquely accountable for prolonging the serum half-life of IgG subclass antibodies and facilitating their passage across cellular barriers. Through these actions, FcRn significantly impacts various aspects of antibody biology and pathobiology. Its crucial role in regulating IgG pharmacokinetics has been exploited in the development of therapeutic antibodies and related biological treatments. Additionally, FcRn is involved in the transport of serum albumin, contributing to the improved pharmacokinetic characteristics of albumin-conjugated therapies. However, a lack of dependable serological tools targeting human FcRn has limited the comprehension of its functions and potential therapeutic uses.
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Antibody clone number
ADM31
Vial size
100 µl
Concentration
1.068 mg/ml
Storage
Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing.
Handling
Wet Ice
FCGRT protein structure - 200-301-MX7 shown in red.