200-301-MX8

antibody from Rockland Immunochemicals, Inc.
Targeting: FCGRT alpha-chain, FCRN
Provider product page for 200-301-MX8
Immunocytochemistry
Flow cytometry

Antibody data

Product number
200-301-MX8 - Provider product page
Provider
Rockland Immunochemicals, Inc.
Product name
Anti-hFcRn (MOUSE) Monoclonal Antibody - 200-301-MX8
Antibody type
Monoclonal
Description
The MHC class I-like Fc receptor (FcRn) is an intracellular trafficking Fc receptor that is uniquely responsible for the extended serum half-life of antibodies of the IgG subclass and their ability to transport across cellular barriers. By performing these functions, FcRn affects numerous facets of antibody biology and pathobiology. Its critical role in controlling IgG pharmacokinetics has been leveraged for the design of therapeutic antibodies and related biologics. FcRn also traffics serum albumin and is responsible for the enhanced pharmacokinetic properties of albumin-conjugated therapeutics.
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Antibody clone number
DVN24
Vial size
100 µl
Concentration
1.082 mg/ml
Storage
Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing.
Handling
Wet Ice
FCGRT protein structure - 200-301-MX8 shown in red.