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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- HPA016646 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA016646, RRID:AB_1845096
- Product name
- Anti-ASL
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human ASL, Gene description: argininosuccinate lyase, Validated applications: IHC, Uniprot ID: P04424, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Characterisation of Expression the Arginine Pathway Enzymes in Childhood Brain Tumours to Determine Susceptibility to Therapeutic Arginine Depletion
ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism
Reconstitution of T Cell Proliferation under Arginine Limitation: Activated Human T Cells Take Up Citrulline via L-Type Amino Acid Transporter 1 and Use It to Regenerate Arginine after Induction of Argininosuccinate Synthase Expression
Inhibition of the Polyamine Synthesis Pathway Is Synthetically Lethal with Loss of Argininosuccinate Synthase 1
Aberrant Expression and Distribution of Enzymes of the Urea Cycle and Other Ammonia Metabolizing Pathways in Dogs with Congenital Portosystemic Shunts
Bishop E, Dimitrova M, Froggatt A, Estevez-Cebrero M, Storer L, Mussai F, Paine S, Grundy R, Dandapani M, Prodam F
BioMed Research International 2022;2022(1)
BioMed Research International 2022;2022(1)
ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism
Khare S, Kim L, Lobel G, Doulias P, Ischiropoulos H, Nissim I, Keith B, Simon M
Cancer & Metabolism 2021;9(1)
Cancer & Metabolism 2021;9(1)
Reconstitution of T Cell Proliferation under Arginine Limitation: Activated Human T Cells Take Up Citrulline via L-Type Amino Acid Transporter 1 and Use It to Regenerate Arginine after Induction of Argininosuccinate Synthase Expression
Werner A, Koschke M, Leuchtner N, Luckner-Minden C, Habermeier A, Rupp J, Heinrich C, Conradi R, Closs E, Munder M
Frontiers in Immunology 2017;8
Frontiers in Immunology 2017;8
Inhibition of the Polyamine Synthesis Pathway Is Synthetically Lethal with Loss of Argininosuccinate Synthase 1
Locke M, Ghazaly E, Freitas M, Mitsinga M, Lattanzio L, Lo Nigro C, Nagano A, Wang J, Chelala C, Szlosarek P, Martin S
Cell Reports 2016;16(6):1604-1613
Cell Reports 2016;16(6):1604-1613
Aberrant Expression and Distribution of Enzymes of the Urea Cycle and Other Ammonia Metabolizing Pathways in Dogs with Congenital Portosystemic Shunts
Blachier F, van Straten G, van Steenbeek F, Grinwis G, Favier R, Kummeling A, van Gils I, Fieten H, Groot Koerkamp M, Holstege F, Rothuizen J, Spee B
PLoS ONE 2014;9(6):e100077
PLoS ONE 2014;9(6):e100077
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human liver and skeletal muscle tissues using HPA016646 antibody. Corresponding ASL RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
