Tissue expression
Cell line expression
Protein structure
PSMD11
Proteasome 26S subunit, non-ATPase 11MGC3844, p44.5, Rpn6, S9
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Top validated antibodies |
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Proteintech Group | 14786-1-AP | 8 references | Polyclonal |
WB
EL
ICC
IP |
|
Invitrogen Antibodies | 14786-1-AP | Polyclonal |
WB
ICC
IP
OA |
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Novus Biologicals | NBP2-59484-100ul | Monoclonal |
WB
EL
ICC
FC |
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NovoPro Bioscience Inc. | 114394 | Polyclonal |
WB
EL
ICC
IP |
||
FineTest Biotech | FNab06883 | Polyclonal |
WB
EL
ICC
IP |
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