Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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Validation data
Reference
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- Product number
- 14786-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14786-1-AP, RRID:AB_2268979
- Product name
- PSMD11 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PSMD11 antibody (Cat. #14786-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Osimertinib resistance-based immune prognostic related gene signature in EGFR mutant lung adenocarcinoma, in which PSMD11 promotes tumor progression.
A large-scale sORF screen identifies putative microproteins involved in cancer cell fitness.
[PSMD11 overexpression promotes epithelial-mesenchymal transition in gastric cancer and affects patient prognosis].
PSMD11 promotes the proliferation of hepatocellular carcinoma by regulating the ubiquitination degradation of CDK4.
Knockout of PA200 improves proteasomal degradation and myelination in a proteotoxic neuropathy.
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system.
Target Fishing Reveals a Novel Mechanism of 1,2,4-Oxadiazole Derivatives Targeting Rpn6, a Subunit of 26S Proteasome.
Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses.
Generation and identification of a conditional knockout allele for the PSMD11 gene in mice.
Susceptibility of microtubule-associated protein 1 light chain 3β (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.
Homoharringtonine could induce quick protein synthesis of PSMD11 through activating MEK1/ERK1/2 signaling pathway in pancreatic cancer cells.
The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.
Proteomic profiling identified multiple short-lived members of the central proteome as the direct targets of the addicted oncogenes in cancer cells.
Bai Y, Xu H, Bao P, Gao Y, Sun J, Shen Y, Zhao J, Jiang T
Translational lung cancer research 2025 Sep 30;14(9):3720-3739
Translational lung cancer research 2025 Sep 30;14(9):3720-3739
A large-scale sORF screen identifies putative microproteins involved in cancer cell fitness.
Schlesinger D, Dirks C, Navarro C, Lafranchi L, Spinner A, Raja GL, Mun-Sum Tong G, Eirich J, Martinez TF, Elsässer SJ
iScience 2025 Mar 21;28(3):111884
iScience 2025 Mar 21;28(3):111884
[PSMD11 overexpression promotes epithelial-mesenchymal transition in gastric cancer and affects patient prognosis].
Zhou R, Yang J, Song B, Chen X, Wang L, Wang Y, Zuo L, Zhu B
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Dec 20;45(12):2747-2755
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Dec 20;45(12):2747-2755
PSMD11 promotes the proliferation of hepatocellular carcinoma by regulating the ubiquitination degradation of CDK4.
Sun L, Liu Z, Wu Z, Wu Z, Qiu B, Liu S, Hu J, Yin X
Cellular signalling 2024 Sep;121:111279
Cellular signalling 2024 Sep;121:111279
Knockout of PA200 improves proteasomal degradation and myelination in a proteotoxic neuropathy.
VerPlank JJ, Gawron JM, Silvestri NJ, Wrabetz L, Feltri ML
Life science alliance 2024 Apr;7(4)
Life science alliance 2024 Apr;7(4)
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system.
Saha I, Yuste-Checa P, Da Silva Padilha M, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Hartl FU, Hipp MS
Nature communications 2023 Feb 2;14(1):560
Nature communications 2023 Feb 2;14(1):560
Target Fishing Reveals a Novel Mechanism of 1,2,4-Oxadiazole Derivatives Targeting Rpn6, a Subunit of 26S Proteasome.
Dai Z, An LY, Chen XY, Yang F, Zhao N, Li CC, Ren R, Li BY, Tao WY, Li P, Jiang C, Yan F, Jiang ZY, You QD, Di B, Xu LL
Journal of medicinal chemistry 2022 Mar 24;65(6):5029-5043
Journal of medicinal chemistry 2022 Mar 24;65(6):5029-5043
Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses.
Gao W, Rui Y, Li G, Zhai C, Su J, Liu H, Zheng W, Zheng B, Zhang W, Yang Y, Hua S, Yu X
Frontiers in immunology 2021;12:740713
Frontiers in immunology 2021;12:740713
Generation and identification of a conditional knockout allele for the PSMD11 gene in mice.
Zhao L, Zhao J, Zhang Y, Wang L, Zuo L, Niu A, Zhang W, Xue X, Zhao S, Sun C, Li K, Wang J, Bian Z, Zhao X, Saur D, Seidler B, Wang C, Qi T
BMC developmental biology 2021 Feb 1;21(1):4
BMC developmental biology 2021 Feb 1;21(1):4
Susceptibility of microtubule-associated protein 1 light chain 3β (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.
Kesireddy VS, Chillappagari S, Ahuja S, Knudsen L, Henneke I, Graumann J, Meiners S, Ochs M, Ruppert C, Korfei M, Seeger W, Mahavadi P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12392-12408
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12392-12408
Homoharringtonine could induce quick protein synthesis of PSMD11 through activating MEK1/ERK1/2 signaling pathway in pancreatic cancer cells.
Wang L, Zhao L, Wei G, Saur D, Seidler B, Wang J, Wang C, Qi T
Journal of cellular biochemistry 2018 Aug;119(8):6644-6656
Journal of cellular biochemistry 2018 Aug;119(8):6644-6656
The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.
Sparks A, Dayal S, Das J, Robertson P, Menendez S, Saville MK
Oncogene 2014 Sep 18;33(38):4685-96
Oncogene 2014 Sep 18;33(38):4685-96
Proteomic profiling identified multiple short-lived members of the central proteome as the direct targets of the addicted oncogenes in cancer cells.
Qi T, Zhang W, Luan Y, Kong F, Xu D, Cheng G, Wang Y
Molecular & cellular proteomics : MCP 2014 Jan;13(1):49-62
Molecular & cellular proteomics : MCP 2014 Jan;13(1):49-62
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14786-1-AP(PSMD11 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The PSMD11 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PSMD11. This antibody recognizes human,mouse,rat antigen. The PSMD11 antibody has been validated for the following applications: ELISA, WB, IP analysis.