FNab05123

antibody from FineTest Biotech
Targeting: MEN1
Provider product page for FNab05123
Western blot
ELISA

Antibody data

Product number
FNab05123 - Provider product page
Provider
FineTest Biotech
Product name
MEN1 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Essential component of a MLL/SET1 histone methyltransferase(HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3(H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression(By similarity). May be involved in DNA repair.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
multiple endocrine neoplasia I
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
MEN1 protein structure - FNab05123 shown in red.