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- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 24641-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- TOP2A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TOP2A antibody (Cat. #24641-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Single-cell RNA profiling reveals classification and characteristics of mononuclear phagocytes in colorectal cancer.
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation.
Chemotherapy- and Immune-Related Gene Panel in Prognosis Prediction and Immune Microenvironment of SCLC.
Kinase activity profiling identifies putative downstream targets of cGMP/PKG signaling in inherited retinal neurodegeneration.
High prevalence of developmental venous anomaly in adult patients with midline thalamic diffuse gliomas.
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
SPOP is essential for DNA-protein cross-link repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.
Identification of a key role for permeability glycoprotein in enhancing the cellular defense mechanisms of fertilized oocytes.
SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.
Anticancer effects of β-elemene in gastric cancer cells and its potential underlying proteins: a proteomic study.
Ji T, Fu H, Wang L, Chen J, Tian S, Wang G, Wang L, Wang Z
PLoS genetics 2024 Feb;20(2):e1011176
PLoS genetics 2024 Feb;20(2):e1011176
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
Chen C, Ye L, Yi J, Liu T, Li Z
Breast cancer research and treatment 2023 Oct;201(3):515-533
Breast cancer research and treatment 2023 Oct;201(3):515-533
Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation.
Muneer A, Wang L, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Jain K, Strahl BD, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
Cell chemical biology 2023 Dec 21;30(12):1525-1541.e7
Cell chemical biology 2023 Dec 21;30(12):1525-1541.e7
Chemotherapy- and Immune-Related Gene Panel in Prognosis Prediction and Immune Microenvironment of SCLC.
Chen MY, Zeng YC, Zhao XH
Frontiers in cell and developmental biology 2022;10:893490
Frontiers in cell and developmental biology 2022;10:893490
Kinase activity profiling identifies putative downstream targets of cGMP/PKG signaling in inherited retinal neurodegeneration.
Roy A, Tolone A, Hilhorst R, Groten J, Tomar T, Paquet-Durand F
Cell death discovery 2022 Mar 3;8(1):93
Cell death discovery 2022 Mar 3;8(1):93
High prevalence of developmental venous anomaly in adult patients with midline thalamic diffuse gliomas.
Zhou X, Niu X, Mao Q, Liu Y
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2021 May;87:59-65
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2021 May;87:59-65
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Wang L, Muneer A, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Gheorghe C, Torralba K, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
bioRxiv : the preprint server for biology 2020 Nov 16;
bioRxiv : the preprint server for biology 2020 Nov 16;
SPOP is essential for DNA-protein cross-link repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.
Watanabe R, Maekawa M, Hieda M, Taguchi T, Miura N, Kikugawa T, Saika T, Higashiyama S
Molecular biology of the cell 2020 Mar 15;31(6):478-490
Molecular biology of the cell 2020 Mar 15;31(6):478-490
Identification of a key role for permeability glycoprotein in enhancing the cellular defense mechanisms of fertilized oocytes.
Martin JH, Nixon B, Lord T, Bromfield EG, Aitken RJ
Developmental biology 2016 Sep 1;417(1):63-76
Developmental biology 2016 Sep 1;417(1):63-76
SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.
Wu J, Yang C, Guo C, Li X, Yang N, Zhao L, Hang H, Liu S, Chu P, Sun Z, Sun B, Lin Y, Peng J, Han G, Wang S, Tang Z
Chemico-biological interactions 2016 Jan 25;244:94-104
Chemico-biological interactions 2016 Jan 25;244:94-104
Anticancer effects of β-elemene in gastric cancer cells and its potential underlying proteins: a proteomic study.
Liu JS, He SC, Zhang ZL, Chen R, Fan L, Qiu GL, Chang S, Li L, Che XM
Oncology reports 2014 Dec;32(6):2635-47
Oncology reports 2014 Dec;32(6):2635-47
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 24641-1-AP( TOP2A Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TOP2A antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TOP2A. This antibody recognizes human antigen. The TOP2A antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
