Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN1109282 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (N-Term) antibody
- Antibody type
- Monoclonal
- Description
- Protein-A Sepharose
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Epitope
- N-Term
- Isotype
- IgG
- Antibody clone number
- AK5
- Vial size
- 0.1 mg
- Storage
- Store (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Protein kinase C delta activates topoisomerase IIalpha to induce apoptotic cell death in response to DNA damage.
Human herpesvirus 6 open reading frame U14 protein and cellular p53 interact with each other and are contained in the virion.
An atypical topoisomerase II from Archaea with implications for meiotic recombination.
Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family.
Degradation of topoisomerase IIalpha during adenovirus E1A-induced apoptosis is mediated by the activation of the ubiquitin proteolysis system.
Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis.
Molecular cloning of partial cDNAs for rat DNA topoisomerase II isoforms and their differential expression in brain development.
Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22.
Yoshida K, Yamaguchi T, Shinagawa H, Taira N, Nakayama KI, Miki Y
Molecular and cellular biology 2006 May;26(9):3414-31
Molecular and cellular biology 2006 May;26(9):3414-31
Human herpesvirus 6 open reading frame U14 protein and cellular p53 interact with each other and are contained in the virion.
Takemoto M, Koike M, Mori Y, Yonemoto S, Sasamoto Y, Kondo K, Uchiyama Y, Yamanishi K
Journal of virology 2005 Oct;79(20):13037-46
Journal of virology 2005 Oct;79(20):13037-46
An atypical topoisomerase II from Archaea with implications for meiotic recombination.
Bergerat A, de Massy B, Gadelle D, Varoutas PC, Nicolas A, Forterre P
Nature 1997 Mar 27;386(6623):414-7
Nature 1997 Mar 27;386(6623):414-7
Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family.
Keeney S, Giroux CN, Kleckner N
Cell 1997 Feb 7;88(3):375-84
Cell 1997 Feb 7;88(3):375-84
Degradation of topoisomerase IIalpha during adenovirus E1A-induced apoptosis is mediated by the activation of the ubiquitin proteolysis system.
Nakajima T, Morita K, Ohi N, Arai T, Nozaki N, Kikuchi A, Osaka F, Yamao F, Oda K
The Journal of biological chemistry 1996 Oct 4;271(40):24842-9
The Journal of biological chemistry 1996 Oct 4;271(40):24842-9
Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis.
Casiano CA, Martin SJ, Green DR, Tan EM
The Journal of experimental medicine 1996 Aug 1;184(2):765-70
The Journal of experimental medicine 1996 Aug 1;184(2):765-70
Molecular cloning of partial cDNAs for rat DNA topoisomerase II isoforms and their differential expression in brain development.
Tsutsui K, Tsutsui K, Okada S, Watanabe M, Shohmori T, Seki S, Inoue Y
The Journal of biological chemistry 1993 Sep 5;268(25):19076-83
The Journal of biological chemistry 1993 Sep 5;268(25):19076-83
Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22.
Tsai-Pflugfelder M, Liu LF, Liu AA, Tewey KM, Whang-Peng J, Knutsen T, Huebner K, Croce CM, Wang JC
Proceedings of the National Academy of Sciences of the United States of America 1988 Oct;85(19):7177-81
Proceedings of the National Academy of Sciences of the United States of America 1988 Oct;85(19):7177-81
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB