DMAB7027

antibody from Creative Diagnostics

Targeting: TOP2A TOP2

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DMAB7027

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DMAB7027, RRID:AB_2396404

Product name

Anti-Topoisomerase II monoclonal antibody, clone 4G7

Antibody type

Monoclonal

Description

Type II topoisomerases cut both strands of the DNA helix simultaneously in order to manage DNA tangles and supercoils. They use the hydrolysis of ATP, unlike type I topoisomerase. In this process, these enzymes change the linking number of circular DNA by +/-2.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

4G7

Storage

Lyophilized product, 5 years at 2 - 8 oC. Solution, 2 years at -20 oC.