Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- NBP2-47643-0.02mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal TOP2A Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. It recognizes a 170kDa protein, which is identified as topoisomerase IIa. It shows no cross-reaction with Topoisomerase IIb or I. Topo IIa plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIa is also implicated in drug resistance of tumor cells.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.02 mg
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TOP2A Antibody (TOP2A/1361) [NBP2-47643] - HepG2, HeLa and 3T3 Cell Lysate using Topo II alpha, Monoclonal Antibody (TOP2A/1361).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TOP2A Antibody (TOP2A/1361) [NBP2-47643] - Formalin-fixed, paraffin-embedded Human Bladder Carcinoma stained with Topoisomerase II alpha Monoclonal Antibody (TOP2A/1361).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TOP2A Antibody (TOP2A/1361) [NBP2-47643] - Formalin-fixed, paraffin-embedded Human Tonsil stained with Topoisomerase II alpha Monoclonal Antibody (TOP2A/1361).