Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN1109281 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) antibody
- Antibody type
- Monoclonal
- Description
- Supernatant
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 8D2
- Vial size
- 0.1 mL
- Storage
- Store at 2 - 8°C.
Submitted references Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.
The RNA binding activity of a ribosome biogenesis factor, nucleophosmin/B23, is modulated by phosphorylation with a cell cycle-dependent kinase and by association with its subtype.
Akt enhances Mdm2-mediated ubiquitination and degradation of p53.
Temporal and spatial distribution of DNA topoisomerase II alters during proliferation, differentiation, and apoptosis in HL-60 cells.
Degradation of topoisomerase IIalpha during adenovirus E1A-induced apoptosis is mediated by the activation of the ubiquitin proteolysis system.
Identification of an interferon-gamma receptor alpha chain sequence required for JAK-1 binding.
Identification of the nature of modification that causes the shift of DNA topoisomerase II beta to apparent higher molecular weight forms in the M phase.
Sakaguchi A, Kikuchi A
Journal of cell science 2004 Mar 1;117(Pt 7):1047-54
Journal of cell science 2004 Mar 1;117(Pt 7):1047-54
The RNA binding activity of a ribosome biogenesis factor, nucleophosmin/B23, is modulated by phosphorylation with a cell cycle-dependent kinase and by association with its subtype.
Okuwaki M, Tsujimoto M, Nagata K
Molecular biology of the cell 2002 Jun;13(6):2016-30
Molecular biology of the cell 2002 Jun;13(6):2016-30
Akt enhances Mdm2-mediated ubiquitination and degradation of p53.
Ogawara Y, Kishishita S, Obata T, Isazawa Y, Suzuki T, Tanaka K, Masuyama N, Gotoh Y
The Journal of biological chemistry 2002 Jun 14;277(24):21843-50
The Journal of biological chemistry 2002 Jun 14;277(24):21843-50
Temporal and spatial distribution of DNA topoisomerase II alters during proliferation, differentiation, and apoptosis in HL-60 cells.
Sugimoto K, Yamada K, Egashira M, Yazaki Y, Hirai H, Kikuchi A, Oshimi K
Blood 1998 Feb 15;91(4):1407-17
Blood 1998 Feb 15;91(4):1407-17
Degradation of topoisomerase IIalpha during adenovirus E1A-induced apoptosis is mediated by the activation of the ubiquitin proteolysis system.
Nakajima T, Morita K, Ohi N, Arai T, Nozaki N, Kikuchi A, Osaka F, Yamao F, Oda K
The Journal of biological chemistry 1996 Oct 4;271(40):24842-9
The Journal of biological chemistry 1996 Oct 4;271(40):24842-9
Identification of an interferon-gamma receptor alpha chain sequence required for JAK-1 binding.
Kaplan DH, Greenlund AC, Tanner JW, Shaw AS, Schreiber RD
The Journal of biological chemistry 1996 Jan 5;271(1):9-12
The Journal of biological chemistry 1996 Jan 5;271(1):9-12
Identification of the nature of modification that causes the shift of DNA topoisomerase II beta to apparent higher molecular weight forms in the M phase.
Kimura K, Nozaki N, Saijo M, Kikuchi A, Ui M, Enomoto T
The Journal of biological chemistry 1994 Oct 7;269(40):24523-6
The Journal of biological chemistry 1994 Oct 7;269(40):24523-6
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Supportive validation
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC