Explore
Validate
Learn
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- HPA006458 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA006458, RRID:AB_1858189
- Product name
- Anti-TOP2A
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human TOP2A, Gene description: topoisomerase (DNA) II alpha 170kDa, Alternative Gene Names: TOP2, Validated applications: WB, IHC, Uniprot ID: P11388, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Study on the expression of TOP2A in hepatocellular carcinoma and its relationship with patient prognosis
A Gene Co-Expression Network-Based Drug Repositioning Approach Identifies Candidates for Treatment of Hepatocellular Carcinoma
Transcriptome analysis revealed key prognostic genes and microRNAs in hepatocellular carcinoma
TOP2A and CENPF are synergistic master regulators activated in cervical cancer
Transcriptome Analysis Revealed a Highly Connected Gene Module Associated With Cirrhosis to Hepatocellular Carcinoma Development
The microRNA expression signature of small cell lung cancer: tumor suppressors of miR-27a-5p and miR-34b-3p and their targeted oncogenes
Tumour expression of bladder cancer‐associated urinary proteins
Antibodies Biotinylated Using a Synthetic Z-domain from Protein A Provide Stringent In Situ Protein Detection
Antibodies biotinylated using a synthetic Z-domain from protein A provide stringent in situ protein detection.
Meng J, Wei Y, Deng Q, Li L, Li X
Cancer Cell International 2022;22(1)
Cancer Cell International 2022;22(1)
A Gene Co-Expression Network-Based Drug Repositioning Approach Identifies Candidates for Treatment of Hepatocellular Carcinoma
Yuan M, Shong K, Li X, Ashraf S, Shi M, Kim W, Nielsen J, Turkez H, Shoaie S, Uhlen M, Zhang C, Mardinoglu A
Cancers 2022;14(6):1573
Cancers 2022;14(6):1573
Transcriptome analysis revealed key prognostic genes and microRNAs in hepatocellular carcinoma
Ma X, Zhou L, Zheng S
PeerJ 2020;8
PeerJ 2020;8
TOP2A and CENPF are synergistic master regulators activated in cervical cancer
Yu B, Chen L, Zhang W, Li Y, Zhang Y, Gao Y, Teng X, Zou L, Wang Q, Jia H, Liu X, Zheng H, Hou P, Yu H, Sun Y, Zhang Z, Zhang P, Zhang L
BMC Medical Genomics 2020;13(1)
BMC Medical Genomics 2020;13(1)
Transcriptome Analysis Revealed a Highly Connected Gene Module Associated With Cirrhosis to Hepatocellular Carcinoma Development
Shan S, Chen W, Jia J
Frontiers in Genetics 2019;10
Frontiers in Genetics 2019;10
The microRNA expression signature of small cell lung cancer: tumor suppressors of miR-27a-5p and miR-34b-3p and their targeted oncogenes
Mizuno K, Mataki H, Arai T, Okato A, Kamikawaji K, Kumamoto T, Hiraki T, Hatanaka K, Inoue H, Seki N
Journal of Human Genetics 2017;62(7):671-678
Journal of Human Genetics 2017;62(7):671-678
Tumour expression of bladder cancer‐associated urinary proteins
Lindén M, Segersten U, Runeson M, Wester K, Busch C, Pettersson U, Lind S, Malmström P
BJU International 2013;112(3):407-415
BJU International 2013;112(3):407-415
Antibodies Biotinylated Using a Synthetic Z-domain from Protein A Provide Stringent In Situ Protein Detection
Andersson S, Konrad A, Ashok N, Ponten F, Hober S, Asplund A
Journal of Histochemistry & Cytochemistry 2013 October;61(11):773-784
Journal of Histochemistry & Cytochemistry 2013 October;61(11):773-784
Antibodies biotinylated using a synthetic Z-domain from protein A provide stringent in situ protein detection.
Andersson S, Konrad A, Ashok N, Pontén F, Hober S, Asplund A
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2013 Nov;61(11):773-84
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2013 Nov;61(11):773-84
No comments: Submit comment
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human testis and liver tissues using HPA006458 antibody. Corresponding TOP2A RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
