DMAB6360

antibody from Creative Diagnostics

Targeting: C5 C5a, C5b, CPAMD4

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

DMAB6360

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DMAB6360, RRID:AB_2395803

Product name

Anti-Complement C5b monoclonal antibody, clone IDD6c.2

Antibody type

Monoclonal

Description

Activation of the complement system plays a key role in normal inflammatory response to injury but may cause substantial injury when activated inappropriately. The complement system is activated either through the classical (antibody induced) or the alternative (microbial surface, polysacharride induced) pathway, both leading to the formation of the C5b9 complex. Fluid phase binding of the multifunctional glycoprotein S protein (vitronectin) to C5b9 leads to the formation of a cytolytically inactive complex, SC5b9, which is unable to attach to cells.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

IDD6c.2

Vial size

1 ea

Storage

At 2-8°C one year after reconstitution.