Tissue expression
Cell line expression
Protein structure

C5

Complement C5
C5a, C5b, CPAMD4 
This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
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959 antibodies from 43 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
77 antibodies
R&D Systems
10 antibodies
antibodies-online
175 antibodies
Aviva Systems Biology
4 antibodies
Proteintech Group
1 antibody
OriGene
17 antibodies
Invitrogen Antibodies
51 antibodies
NSJ Bioreagents
5 antibodies
NovoPro Bioscience Inc.
2 antibodies
Abgent
3 antibodies
Boster Biological Technology
1 antibody
GeneTex
14 antibodies
Aladdin Scientific Corporation
3 antibodies
Exalpha Biologicals, Inc.
2 antibodies
St John's Laboratory
2 antibodies
BioLegend
8 antibodies
Creative Biolabs
337 antibodies
Abbiotec
3 antibodies
ProSci
1 antibody
Signalway Antibody LLC
1 antibody
Acris Antibodies GmbH
18 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
RabMAbs
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Affinity Biosciences
1 antibody
Antibodies.com
1 antibody
Creative Diagnostics
21 antibodies
Kerafast Inc.
3 antibodies
MyBioSource
9 antibodies
Arigo
1 antibody
Atlas Antibodies
1 antibody
Abbexa
13 antibodies
United States Biological
14 antibodies
Absolute Antibody
25 antibodies
Sino Biological Inc.
5 antibodies
Leading Biology
2 antibodies
GenWay
3 antibodies
Enzo Life Sciences
5 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
RayBiotech, Inc.
1 antibody
Abnova Corporation
2 antibodies