CDCA7

This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Description

Cell division cycle associated 7

Tissue specificity

Tissue enhanced (intestine, lymphoid tissue)

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

2 (173354820 - 173368997)

Ensembl ID

ENSG00000144354  (ver. 103.38)

Orthologs

Mouse Cdca7: ENSMUSG00000055612

UniProt

Q9BWT1

neXtProt

NX_Q9BWT1

Human splice variants
Mouse splice variants

Protein structure