516703

antibody from BioLegend
Targeting: IL21 IL-21, Za11
Provider product page for 516703

Antibody data

Product number
516703 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#516703, RRID:AB_2125257
Product name
PE anti-human IL-21
Antibody type
Monoclonal
Antigen
IL-21
Description
Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset and has pleiotropic effects on both innate and adaptive immune responses.  These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells.  It can also be proapoptotic for B cells and NK cells.  Recent studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
IL21 protein structure - 516703 shown in red.