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Cell line expression
Protein structure
IL21
Interleukin 21IL-21, Za11
This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Top validated antibodies |
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| R&D Systems |  AF594 |
14 references | Polyclonal |
WB
EL
ICC
BN
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| antibodies-online | ABIN315232 |
5 references | Polyclonal |
WB
ICC
IHC
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| Novus Biologicals | AF594 |
15 references | Polyclonal |
WB
ICC
BN
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| Proteintech Group | 17625-1-AP |
4 references | Polyclonal |
WB
EL
IHC
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| Invitrogen Antibodies | PA5-34801 |
3 references | Polyclonal |
WB
IHC
OA
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