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- Antigen structure
- References [19]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10984-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10984-1-AP, RRID:AB_2146488
- Product name
- MRPS22 antibody
- Antibody type
- Polyclonal
- Description
- MRPS22 antibody (Cat. #10984-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Germ cell-specific deletion of Pex3 reveals essential roles of PEX3-dependent peroxisomes in spermiogenesis.
Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival.
Messenger RNA delivery to mitoribosomes - hints from a bacterial toxin.
MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition.
Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB.
Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency.
Stomatin-like protein 2 deficiency results in impaired mitochondrial translation.
A homozygous missense mutation in ERAL1, encoding a mitochondrial rRNA chaperone, causes Perrault syndrome.
A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability.
Human Mitochondrial DNA-Protein Complexes Attach to a Cholesterol-Rich Membrane Structure.
Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis.
The Human Mitochondrial DEAD-Box Protein DDX28 Resides in RNA Granules and Functions in Mitoribosome Assembly.
The arginine methyltransferase NDUFAF7 is essential for complex I assembly and early vertebrate embryogenesis.
MPV17L2 is required for ribosome assembly in mitochondria.
Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication.
Mutations in the UQCC1-interacting protein, UQCC2, cause human complex III deficiency associated with perturbed cytochrome b protein expression.
The mitochondrial RNA-binding protein GRSF1 localizes to RNA granules and is required for posttranscriptional mitochondrial gene expression.
p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability.
C7orf30 specifically associates with the large subunit of the mitochondrial ribosome and is involved in translation.
Yao Y, Shi B, Zhang X, Wang X, Li S, Yao Y, Guo Y, Chen D, Wang B, Yuan Y, Sha J, Guo X
Journal of biomedical research 2023 Dec 8;38(1):24-36
Journal of biomedical research 2023 Dec 8;38(1):24-36
Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival.
Lowden C, Boulet A, Boehler NA, Seecharran S, Rios Garcia J, Lowe NJ, Liu J, Ong JLK, Wang W, Ma L, Cheng AH, Senatore A, Monks DA, Liu BH, Leary SC, Cheng HM
Cell reports 2021 Sep 14;36(11):109704
Cell reports 2021 Sep 14;36(11):109704
Messenger RNA delivery to mitoribosomes - hints from a bacterial toxin.
Bruni F, Proctor-Kent Y, Lightowlers RN, Chrzanowska-Lightowlers ZM
The FEBS journal 2021 Jan;288(2):437-451
The FEBS journal 2021 Jan;288(2):437-451
MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition.
Busch JD, Cipullo M, Atanassov I, Bratic A, Silva Ramos E, Schöndorf T, Li X, Pearce SF, Milenkovic D, Rorbach J, Larsson NG
Cell reports 2019 Nov 5;29(6):1728-1738.e9
Cell reports 2019 Nov 5;29(6):1728-1738.e9
Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB.
Hensen F, Potter A, van Esveld SL, Tarrés-Solé A, Chakraborty A, Solà M, Spelbrink JN
Nucleic acids research 2019 Apr 23;47(7):3680-3698
Nucleic acids research 2019 Apr 23;47(7):3680-3698
Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency.
Chen A, Tiosano D, Guran T, Baris HN, Bayram Y, Mory A, Shapiro-Kulnane L, Hodges CA, Akdemir ZC, Turan S, Jhangiani SN, van den Akker F, Hoppel CL, Salz HK, Lupski JR, Buchner DA
Human molecular genetics 2018 Jun 1;27(11):1913-1926
Human molecular genetics 2018 Jun 1;27(11):1913-1926
Stomatin-like protein 2 deficiency results in impaired mitochondrial translation.
Mitsopoulos P, Lapohos O, Weraarpachai W, Antonicka H, Chang YH, Madrenas J
PloS one 2017;12(6):e0179967
PloS one 2017;12(6):e0179967
A homozygous missense mutation in ERAL1, encoding a mitochondrial rRNA chaperone, causes Perrault syndrome.
Chatzispyrou IA, Alders M, Guerrero-Castillo S, Zapata Perez R, Haagmans MA, Mouchiroud L, Koster J, Ofman R, Baas F, Waterham HR, Spelbrink JN, Auwerx J, Mannens MM, Houtkooper RH, Plomp AS
Human molecular genetics 2017 Jul 1;26(13):2541-2550
Human molecular genetics 2017 Jul 1;26(13):2541-2550
A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability.
Antonicka H, Choquet K, Lin ZY, Gingras AC, Kleinman CL, Shoubridge EA
EMBO reports 2017 Jan;18(1):28-38
EMBO reports 2017 Jan;18(1):28-38
Human Mitochondrial DNA-Protein Complexes Attach to a Cholesterol-Rich Membrane Structure.
Gerhold JM, Cansiz-Arda Ş, Lõhmus M, Engberg O, Reyes A, van Rennes H, Sanz A, Holt IJ, Cooper HM, Spelbrink JN
Scientific reports 2015 Oct 19;5:15292
Scientific reports 2015 Oct 19;5:15292
Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis.
Antonicka H, Shoubridge EA
Cell reports 2015 Feb 17;10(6):920-932
Cell reports 2015 Feb 17;10(6):920-932
The Human Mitochondrial DEAD-Box Protein DDX28 Resides in RNA Granules and Functions in Mitoribosome Assembly.
Tu YT, Barrientos A
Cell reports 2015 Feb 17;10(6):854-864
Cell reports 2015 Feb 17;10(6):854-864
The arginine methyltransferase NDUFAF7 is essential for complex I assembly and early vertebrate embryogenesis.
Zurita Rendón O, Silva Neiva L, Sasarman F, Shoubridge EA
Human molecular genetics 2014 Oct 1;23(19):5159-70
Human molecular genetics 2014 Oct 1;23(19):5159-70
MPV17L2 is required for ribosome assembly in mitochondria.
Dalla Rosa I, Durigon R, Pearce SF, Rorbach J, Hirst EM, Vidoni S, Reyes A, Brea-Calvo G, Minczuk M, Woellhaf MW, Herrmann JM, Huynen MA, Holt IJ, Spinazzola A
Nucleic acids research 2014 Jul;42(13):8500-15
Nucleic acids research 2014 Jul;42(13):8500-15
Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication.
Rajala N, Gerhold JM, Martinsson P, Klymov A, Spelbrink JN
Nucleic acids research 2014 Jan;42(2):952-67
Nucleic acids research 2014 Jan;42(2):952-67
Mutations in the UQCC1-interacting protein, UQCC2, cause human complex III deficiency associated with perturbed cytochrome b protein expression.
Tucker EJ, Wanschers BF, Szklarczyk R, Mountford HS, Wijeyeratne XW, van den Brand MA, Leenders AM, Rodenburg RJ, Reljić B, Compton AG, Frazier AE, Bruno DL, Christodoulou J, Endo H, Ryan MT, Nijtmans LG, Huynen MA, Thorburn DR
PLoS genetics 2013;9(12):e1004034
PLoS genetics 2013;9(12):e1004034
The mitochondrial RNA-binding protein GRSF1 localizes to RNA granules and is required for posttranscriptional mitochondrial gene expression.
Antonicka H, Sasarman F, Nishimura T, Paupe V, Shoubridge EA
Cell metabolism 2013 Mar 5;17(3):386-98
Cell metabolism 2013 Mar 5;17(3):386-98
p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability.
Yagi M, Uchiumi T, Takazaki S, Okuno B, Nomura M, Yoshida S, Kanki T, Kang D
Nucleic acids research 2012 Oct;40(19):9717-37
Nucleic acids research 2012 Oct;40(19):9717-37
C7orf30 specifically associates with the large subunit of the mitochondrial ribosome and is involved in translation.
Wanschers BF, Szklarczyk R, Pajak A, van den Brand MA, Gloerich J, Rodenburg RJ, Lightowlers RN, Nijtmans LG, Huynen MA
Nucleic acids research 2012 May;40(9):4040-51
Nucleic acids research 2012 May;40(9):4040-51
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 10984-1-AP(MRPS22 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MRPS22 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MRPS22. This antibody recognizes human antigen. The MRPS22 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
