Tissue expression
Cell line expression
Protein structure
MRPS22
Mitochondrial ribosomal protein S22C3orf5, GIBT, GK002, MRP-S22
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Atlas Antibodies | HPA006083 | 1 references | Polyclonal |
WB
ICC
IHC
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Proteintech Group | 10984-1-AP | 19 references | Polyclonal |
WB
EL
IP
IHC |
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Invitrogen Antibodies | PA5-52249 | 1 references | Polyclonal |
WB
ICC
IHC
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LSBio | LS-C368759 | Polyclonal |
WB
ICC
IHC
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Novus Biologicals | NBP1-86787 | 1 references | Polyclonal |
WB
ICC
IHC
|
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