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Western blot
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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Immunocytochemistry [1]
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- Product number
- PA5-52249 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- MRPS22 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: TKKPTFMDEE VQSILTKMTG LNLQKTFKPA IQELKPPTYK LMTQAQLEEA TRQAVEAAKV RLKMPPVLEE RVPINDVLAE DKILEGTETT KYVFTDISYS IPHRERFIVV REPSGTLRKA Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 93%.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.2 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis.
Baechler SA, Factor VM, Dalla Rosa I, Ravji A, Becker D, Khiati S, Miller Jenkins LM, Lang M, Sourbier C, Michaels SA, Neckers LM, Zhang HL, Spinazzola A, Huang SN, Marquardt JU, Pommier Y
Nature communications 2019 Jan 8;10(1):83
Nature communications 2019 Jan 8;10(1):83
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Supportive validation
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of MRPS22 in human cell line U-2 OS shows positivity in mitochondria. Samples were probed using a MRPS22 Polyclonal Antibody (Product # PA5-52249).
