Tissue expression
Cell line expression
Protein structure

CBLB

Cbl proto-oncogene B
Cbl-b, RNF56 
This gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell receptor, and high affinity immunoglobulin epsilon receptor activation. Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and infections. [provided by RefSeq, Sep 2017]
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281 antibodies from 33 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
3 antibodies
antibodies-online
78 antibodies
Invitrogen Antibodies
16 antibodies
NovoPro Bioscience Inc.
1 antibody
Aviva Systems Biology
1 antibody
Biorbyt
25 antibodies
Atlas Antibodies
2 antibodies
Abgent
1 antibody
Cusabio Biotech Co., Ltd
1 antibody
Novus Biologicals
6 antibodies
Affinity Biosciences
1 antibody
FineTest Biotech
1 antibody
Abnova Corporation
3 antibodies
GeneTex
2 antibodies
Bioworld Technology, Inc
1 antibody
Boster Biological Technology
1 antibody
ProSci
1 antibody
Bethyl Laboratories
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
St John's Laboratory
2 antibodies
Creative Diagnostics
3 antibodies
MyBioSource
6 antibodies
Acris Antibodies GmbH
2 antibodies
OriGene
1 antibody
United States Biological
48 antibodies
Cell Signaling Technology, Inc
2 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Leading Biology
1 antibody
RabMAbs
1 antibody
Abbexa
5 antibodies
Creative Biolabs
6 antibodies