Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PA5-16789 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-ErbB4 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- PA5-16789 targets HER-4 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-16789 immunogen is a synthetic peptide from C-terminus of human c-erbB-4 protein.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 500 µL
- Concentration
- 0.2 mg/mL
- Storage
- 4° C
Submitted references EGFR family and cMet expression profiles and prognostic significance in esophagogastric adenocarcinoma.
Expression of the EGF family in gastric cancer: downregulation of HER4 and its activating ligand NRG4.
Prognostic value of epidermal growth factor receptors in gastric cancer: a survival analysis by Weibull model incorporating long-term survivors.
Characterisation of HER heterodimers in breast cancer using in situ proximity ligation assay.
The HER4 isoform JM-a/CYT2 relates to improved survival in bladder cancer patients but only if the estrogen receptor α is not expressed.
Evaluation of the antitumor activity of dacomitinib in models of human bladder cancer.
Assessment of protein expression and gene status of human epidermal growth factor receptor (HER) family molecules in ameloblastomas.
Immunohistochemical analysis of the monoclonal antibody 4B5 in breast tissue expressing human epidermal growth factor receptor 4 (HER4).
Activated HER-receptors in predicting outcome of ER-positive breast cancer patients treated with adjuvant endocrine therapy.
Chan E, Alkhasawneh A, Duckworth LV, Aijaz T, Toro TZ, Lu X, Hughes SJ, Collinsworth A, George TJ Jr
Journal of gastrointestinal oncology 2016 Dec;7(6):838-847
Journal of gastrointestinal oncology 2016 Dec;7(6):838-847
Expression of the EGF family in gastric cancer: downregulation of HER4 and its activating ligand NRG4.
Nielsen TO, Friis-Hansen L, Poulsen SS, Federspiel B, Sorensen BS
PloS one 2014;9(4):e94606
PloS one 2014;9(4):e94606
Prognostic value of epidermal growth factor receptors in gastric cancer: a survival analysis by Weibull model incorporating long-term survivors.
Jácome AA, Wohnrath DR, Scapulatempo Neto C, Carneseca EC, Serrano SV, Viana LS, Nunes JS, Martinez EZ, Santos JS
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2014 Jan;17(1):76-86
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2014 Jan;17(1):76-86
Characterisation of HER heterodimers in breast cancer using in situ proximity ligation assay.
Barros FF, Abdel-Fatah TM, Moseley P, Nolan CC, Durham AC, Rakha EA, Chan S, Ellis IO, Green AR
Breast cancer research and treatment 2014 Apr;144(2):273-85
Breast cancer research and treatment 2014 Apr;144(2):273-85
The HER4 isoform JM-a/CYT2 relates to improved survival in bladder cancer patients but only if the estrogen receptor α is not expressed.
Munk M, Memon A, Poulsen SS, Borre M, Nexo E, Sorensen BS
Scandinavian journal of clinical and laboratory investigation 2013 Sep;73(6):503-13
Scandinavian journal of clinical and laboratory investigation 2013 Sep;73(6):503-13
Evaluation of the antitumor activity of dacomitinib in models of human bladder cancer.
Grivas PD, Day KC, Karatsinides A, Paul A, Shakir N, Owainati I, Liebert M, Kunju LP, Thomas D, Hussain M, Day ML
Molecular medicine (Cambridge, Mass.) 2013 Nov 8;19:367-76
Molecular medicine (Cambridge, Mass.) 2013 Nov 8;19:367-76
Assessment of protein expression and gene status of human epidermal growth factor receptor (HER) family molecules in ameloblastomas.
Oikawa M, Miki Y, Shimizu Y, Kumamoto H
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2013 May;42(5):424-34
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2013 May;42(5):424-34
Immunohistochemical analysis of the monoclonal antibody 4B5 in breast tissue expressing human epidermal growth factor receptor 4 (HER4).
Jay JI, Brunhoeber PS, Smith MH, Williams RR, Sugarman MC, Free HL, Tast DE
Histopathology 2013 Mar;62(4):563-77
Histopathology 2013 Mar;62(4):563-77
Activated HER-receptors in predicting outcome of ER-positive breast cancer patients treated with adjuvant endocrine therapy.
Larsen MS, Bjerre K, Lykkesfeldt AE, Giobbie-Hurder A, Laenkholm AV, Henriksen KL, Ejlertsen B, Rasmussen BB
Breast (Edinburgh, Scotland) 2012 Oct;21(5):662-8
Breast (Edinburgh, Scotland) 2012 Oct;21(5):662-8
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot of HER-4 using HER-4 Polyclonal Antibody (Product # PA5-16789) on T47D Cells.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded human breast carcinoma stained with c-erbB4 antibody using peroxidase-conjugate and AEC. Note cytoplasmic and cell membrane staining of tumor cells.
