ERBB4

gene product
ALS19, HER4
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
1353 antibodies from 43 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Invitrogen Antibodies
22 antibodies
Novus Biologicals
45 antibodies
GeneTex
13 antibodies
antibodies-online
460 antibodies
Abgent
14 antibodies
R&D Systems
14 antibodies
Biorbyt
81 antibodies
Abnova Corporation
11 antibodies
Affinity Biosciences
6 antibodies
LifeSpan BioSciences, Inc.
299 antibodies
NovoPro Bioscience Inc.
11 antibodies
Arigo
5 antibodies
Aviva Systems Biology
7 antibodies
NSJ Bioreagents
9 antibodies
OriGene
23 antibodies
Boster Biological Technology
4 antibodies
Cell Signaling Technology, Inc
3 antibodies
Proteintech Group
2 antibodies
Acris Antibodies GmbH
21 antibodies
Atlas Antibodies
1 antibody
St John's Laboratory
6 antibodies
Spring Bioscience
4 antibodies
RabMAbs
16 antibodies
FabGennix
3 antibodies
Bioworld Technology, Inc
2 antibodies
Creative Biolabs
44 antibodies
MyBioSource
16 antibodies
ProSci
5 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Creative Diagnostics
8 antibodies
Signalway Antibody LLC
1 antibody
eBioscience, An Affymetrix Company
3 antibodies
EMD Millipore
4 antibodies
GenWay
5 antibodies
Abbiotec
1 antibody
Bethyl Laboratories
1 antibody
United States Biological
92 antibodies
Sigma-Aldrich
5 antibodies
RayBiotech, Inc.
4 antibodies
Abbexa
3 antibodies
Exalpha Biologicals, Inc.
3 antibodies
Sino Biological Inc.
1 antibody