126705

antibody from BioLegend

Targeting: LGALS3 GALIG, LGALS2, MAC-2

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

126705

Provider

BioLegend

Proper citation

BioLegend Cat#126705, RRID:AB_1134016

Product name

PE anti-mouse/human Mac-2 (Galectin-3)

Antibody type

Monoclonal

Antigen

Recombinant (partial) human Galectin-3

Description

Galectin-3 (galactose-specific lectin 3) is a 30-32 kD glycoprotein, also known as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and εBP. It is a member of the animal β-galactoside-binding lectin family that is expressed in the cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3 contains carbohydrate recognition domains and binds to β-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis. Structurally, Galectin-3 possesses NWGR motif that is conserved in the BH-1 domain of the BCL-2 family and functions as an anti-apoptotic molecule.

Reactivity

Human, Mouse

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG

Vial size

50 µg

Concentration

0.2 mg/ml

Storage

The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.