Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 60207-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60207-1-Ig, RRID:AB_10951109
- Product name
- Galectin-3 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated Galectin-3 antibody (Cat. #60207-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1C1B2
- Vial size
- 20ul, 150ul
Submitted references 17β-Estradiol Attenuates LPS-Induced Macrophage Inflammation In Vitro and Sepsis-Induced Vascular Inflammation In Vivo by Upregulating miR-29a-5p Expression.
Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy.
Transcriptomic Analysis Reveals that Atf3/c-Jun/Lgals3 axis is associated with Central Diabetes Insipidus after Hypothalamic Injury.
Galectin‑3 facilitates the proliferation and migration of nasopharyngeal carcinoma cells via activation of the ERK1/2 and Akt signaling pathways, and is positively correlated with the inflammatory state of nasopharyngeal carcinoma.
Tumor cell membrane-based peptide delivery system targeting the tumor microenvironment for cancer immunotherapy and diagnosis.
Pro64His (rs4644) Polymorphism Within Galectin-3 Is a Risk Factor of Differentiated Thyroid Carcinoma and Affects the Transcriptome of Thyrocytes Engineered via CRISPR/Cas9 System.
Yin-xing-tong-mai decoction attenuates atherosclerosis via activating PPARγ-LXRα-ABCA1/ABCG1 pathway.
Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.
Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis.
Fine particulate matter inhibits phagocytosis of macrophages by disturbing autophagy.
Galectin-3 expression and secretion by tumor-associated macrophages in hypoxia promotes breast cancer progression.
Leukemia cells apoptosis by a newly discovered heterogeneous polysaccharide from Angelica sinensis (Oliv.) Diels.
Gasdermin D Drives the Nonexosomal Secretion of Galectin-3, an Insulin Signal Antagonist.
Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension.
Hypermethylation of IFN-γ in oral cancer tissues.
Inhibition of KLF5-Myo9b-RhoA Pathway-Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm.
Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells.
Tongxinluo inhibits neointimal formation by regulating the expression and post-translational modification of KLF5 in macrophages.
miR-155-dependent regulation of mammalian sterile 20-like kinase 2 (MST2) coordinates inflammation, oxidative stress and proliferation in vascular smooth muscle cells.
Zhang ML, Chen H, Yang Z, Zhang MN, Wang X, Zhao K, Li X, Xiu N, Tong F, Wang YX
Mediators of inflammation 2021;2021:9921897
Mediators of inflammation 2021;2021:9921897
Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy.
Eapen VV, Swarup S, Hoyer MJ, Paulo JA, Harper JW
eLife 2021 Sep 29;10
eLife 2021 Sep 29;10
Transcriptomic Analysis Reveals that Atf3/c-Jun/Lgals3 axis is associated with Central Diabetes Insipidus after Hypothalamic Injury.
Zhou M, Ou Y, Wu G, Li K, Peng J, Wang X, Che M, Gong H, Niu P, Liu Y, Feng Z, Qi S
Neuroendocrinology 2021 Nov 11;
Neuroendocrinology 2021 Nov 11;
Galectin‑3 facilitates the proliferation and migration of nasopharyngeal carcinoma cells via activation of the ERK1/2 and Akt signaling pathways, and is positively correlated with the inflammatory state of nasopharyngeal carcinoma.
Li M, Chen YB, Liu F, Qu JQ, Ren LC, Chai J, Tang CE
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
Tumor cell membrane-based peptide delivery system targeting the tumor microenvironment for cancer immunotherapy and diagnosis.
Meng X, Wang J, Zhou J, Tian Q, Qie B, Zhou G, Duan W, Zhu Y
Acta biomaterialia 2021 Jun;127:266-275
Acta biomaterialia 2021 Jun;127:266-275
Pro64His (rs4644) Polymorphism Within Galectin-3 Is a Risk Factor of Differentiated Thyroid Carcinoma and Affects the Transcriptome of Thyrocytes Engineered via CRISPR/Cas9 System.
Corrado A, Aceto R, Silvestri R, Dell'Anno I, Ricci B, Miglietta S, Romei C, Giovannoni R, Poliseno L, Evangelista M, Vitiello M, Cipollini M, Garritano S, Giusti L, Zallocco L, Elisei R, Landi S, Gemignani F
Thyroid : official journal of the American Thyroid Association 2021 Jul;31(7):1056-1066
Thyroid : official journal of the American Thyroid Association 2021 Jul;31(7):1056-1066
Yin-xing-tong-mai decoction attenuates atherosclerosis via activating PPARγ-LXRα-ABCA1/ABCG1 pathway.
Zheng S, Huang H, Li Y, Wang Y, Zheng Y, Liang J, Zhang S, Liu M, Fang Z
Pharmacological research 2021 Jul;169:105639
Pharmacological research 2021 Jul;169:105639
Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.
Zou L, Zhang X, Xiong M, Meng L, Tian Y, Pan L, Yuan X, Chen G, Wang Z, Bu L, Yao Z, Zhang Z, Ye K, Zhang Z
Neurobiology of disease 2021 Jul;154:105326
Neurobiology of disease 2021 Jul;154:105326
Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis.
Yang GS, Zheng B, Qin Y, Zhou J, Yang Z, Zhang XH, Zhao HY, Yang HJ, Wen JK
Theranostics 2020;10(17):7787-7811
Theranostics 2020;10(17):7787-7811
Fine particulate matter inhibits phagocytosis of macrophages by disturbing autophagy.
Li Y, Yong YL, Yang M, Wang W, Qu X, Dang X, Shang D, Shao Y, Liu J, Chang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16716-16735
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16716-16735
Galectin-3 expression and secretion by tumor-associated macrophages in hypoxia promotes breast cancer progression.
Wang L, Li YS, Yu LG, Zhang XK, Zhao L, Gong FL, Yang XX, Guo XL
Biochemical pharmacology 2020 Aug;178:114113
Biochemical pharmacology 2020 Aug;178:114113
Leukemia cells apoptosis by a newly discovered heterogeneous polysaccharide from Angelica sinensis (Oliv.) Diels.
Liu W, Xiao K, Ren L, Sui Y, Chen J, Zhang T, Li XQ, Cao W
Carbohydrate polymers 2020 Aug 1;241:116279
Carbohydrate polymers 2020 Aug 1;241:116279
Gasdermin D Drives the Nonexosomal Secretion of Galectin-3, an Insulin Signal Antagonist.
Chen Y, Wang H, Shen J, Deng R, Yao X, Guo Q, Lu A, Sun B, Zhang Y, Meng G
Journal of immunology (Baltimore, Md. : 1950) 2019 Nov 15;203(10):2712-2723
Journal of immunology (Baltimore, Md. : 1950) 2019 Nov 15;203(10):2712-2723
Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension.
Luo H, Liu B, Zhao L, He J, Li T, Zha L, Li X, Qi Q, Liu Y, Yu Z
Journal of the American Society of Hypertension : JASH 2017 Oct;11(10):673-683.e3
Journal of the American Society of Hypertension : JASH 2017 Oct;11(10):673-683.e3
Hypermethylation of IFN-γ in oral cancer tissues.
Tian S, Jiang C, Liu X, Xu S, Zhang Z, Chen H, Zhang Y, Liu Y, Ma D
Clinical oral investigations 2017 Nov;21(8):2535-2542
Clinical oral investigations 2017 Nov;21(8):2535-2542
Inhibition of KLF5-Myo9b-RhoA Pathway-Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm.
Ma D, Zheng B, Suzuki T, Zhang R, Jiang C, Bai D, Yin W, Yang Z, Zhang X, Hou L, Zhan H, Wen JK
Circulation research 2017 Mar 3;120(5):799-815
Circulation research 2017 Mar 3;120(5):799-815
Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells.
Tummala KS, Brandt M, Teijeiro A, Graña O, Schwabe RF, Perna C, Djouder N
Cell reports 2017 Apr 18;19(3):584-600
Cell reports 2017 Apr 18;19(3):584-600
Tongxinluo inhibits neointimal formation by regulating the expression and post-translational modification of KLF5 in macrophages.
Jiang W, Zheng B, Zhang XH, Yue LY, Liu C, Ma D, Yang Z, Wen JK
American journal of translational research 2016;8(11):4778-4790
American journal of translational research 2016;8(11):4778-4790
miR-155-dependent regulation of mammalian sterile 20-like kinase 2 (MST2) coordinates inflammation, oxidative stress and proliferation in vascular smooth muscle cells.
Yang Z, Zheng B, Zhang Y, He M, Zhang XH, Ma D, Zhang RN, Wu XL, Wen JK
Biochimica et biophysica acta 2015 Jul;1852(7):1477-89
Biochimica et biophysica acta 2015 Jul;1852(7):1477-89
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 60207-1-Ig(Galectin 3 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using LGALS3 antibody 60207-1-lg at 1:50 dilution and Rhodamine-labeled goat anti-mouse IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 60207-1-Ig(Galectin 3 antibody) at dilution of 1:200 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 60207-1-Ig(Galectin 3 antibody) at dilution of 1:200 (under 40x lens)
- Sample type
- tissue