Tissue expression
Cell line expression
Protein structure

PCSK4

Proprotein convertase subtilisin/kexin type 4
DKFZp434B217, MGC34749, PC4, SPC5 
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. The protease is expressed only in the testis, placenta, and ovary. It plays a critical role in fertilization, fetoplacental growth, and embryonic development and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein and pro-insulin-like growth factor II. [provided by RefSeq, Jan 2014]
More gene data

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153 antibodies from 24 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
FineTest Biotech
2 antibodies
Invitrogen Antibodies
7 antibodies
antibodies-online
52 antibodies
Cusabio Biotech Co., Ltd
1 antibody
NovoPro Bioscience Inc.
1 antibody
Abnova Corporation
3 antibodies
Aviva Systems Biology
2 antibodies
GeneTex
2 antibodies
Novus Biologicals
2 antibodies
NSJ Bioreagents
2 antibodies
Atlas Antibodies
1 antibody
OriGene
1 antibody
Boster Biological Technology
1 antibody
MyBioSource
4 antibodies
Creative Diagnostics
3 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
United States Biological
26 antibodies
ProSci
1 antibody
St John's Laboratory
1 antibody
Abbexa
2 antibodies
Creative Biolabs
1 antibody