Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB3943 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3943, RRID:AB_1571235
- Product name
- ANTXR1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of ANTXR1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin.
Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton.
Receptor-specific requirements for anthrax toxin delivery into cells.
Wei W, Lu Q, Chaudry GJ, Leppla SH, Cohen SN
Cell 2006 Mar 24;124(6):1141-54
Cell 2006 Mar 24;124(6):1141-54
Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton.
Werner E, Kowalczyk AP, Faundez V
The Journal of biological chemistry 2006 Aug 11;281(32):23227-36
The Journal of biological chemistry 2006 Aug 11;281(32):23227-36
Receptor-specific requirements for anthrax toxin delivery into cells.
Rainey GJ, Wigelsworth DJ, Ryan PL, Scobie HM, Collier RJ, Young JA
Proceedings of the National Academy of Sciences of the United States of America 2005 Sep 13;102(37):13278-83
Proceedings of the National Academy of Sciences of the United States of America 2005 Sep 13;102(37):13278-83
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of ANTXR1 polyclonal antibody (Cat # PAB3943) in HeLa cell line lysates (35 ug/lane). ANTXR1 (arrow) was detected using the purified polyclonal antibody (1:1000 dilution).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human lung carcinomareacted with ANTXR1 polyclonal antibody (Cat # PAB3943), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)