ANTXR1

gene product
ATR, FLJ10601, FLJ21776, TEM8
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
605 antibodies from 34 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Novus Biologicals
29 antibodies
Invitrogen Antibodies
10 antibodies
antibodies-online
187 antibodies
Abnova Corporation
8 antibodies
Proteintech Group
1 antibody
OriGene
11 antibodies
LifeSpan BioSciences, Inc.
103 antibodies
R&D Systems
2 antibodies
GeneTex
6 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
Acris Antibodies GmbH
16 antibodies
Biorbyt
15 antibodies
Abgent
6 antibodies
ProSci
3 antibodies
Aviva Systems Biology
7 antibodies
NovoPro Bioscience Inc.
3 antibodies
Bioworld Technology, Inc
1 antibody
Arigo
3 antibodies
St John's Laboratory
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Antibodies.com
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
Creative Biolabs
39 antibodies
Atlas Antibodies
1 antibody
MyBioSource
10 antibodies
Abbiotec
2 antibodies
Leading Biology
7 antibodies
Creative Diagnostics
5 antibodies
United States Biological
78 antibodies
Sigma-Aldrich
7 antibodies
GenWay
4 antibodies
RayBiotech, Inc.
1 antibody