Tissue expression
Cell line expression
Protein structure
ANTXR1
ANTXR cell adhesion molecule 1ATR, FLJ10601, FLJ21776, TEM8
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
Top validated antibodies |
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Proteintech Group | 15091-1-AP | 4 references | Polyclonal |
WB
EL
ICC
IHC |
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Novus Biologicals | NB100-56585 | 6 references | Monoclonal |
WB
ICC
IHC
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antibodies-online | ABIN252539 | 4 references | Monoclonal |
WB
ICC
IHC
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LSBio | LS-B13896 | Polyclonal |
WB
ICC
IHC
|
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Boster Biological Technology | A01563 | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider