Tissue expression
Cell line expression
Protein structure

NR0B2

Nuclear receptor subfamily 0 group B member 2
SHP 
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008]
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429 antibodies from 34 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
131 antibodies
NSJ Bioreagents
3 antibodies
Invitrogen Antibodies
30 antibodies
Abgent
2 antibodies
Novus Biologicals
27 antibodies
OriGene
26 antibodies
GeneTex
5 antibodies
Aviva Systems Biology
6 antibodies
Abnova Corporation
5 antibodies
Acris Antibodies GmbH
3 antibodies
Affinity Biosciences
1 antibody
ProSci
4 antibodies
Signalway Antibody LLC
1 antibody
NovoPro Bioscience Inc.
1 antibody
Enzo Life Sciences
2 antibodies
Bioworld Technology, Inc
1 antibody
St John's Laboratory
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Boster Biological Technology
1 antibody
R&D Systems
1 antibody
United States Biological
41 antibodies
RabMAbs
1 antibody
Cusabio Biotech Co., Ltd
4 antibodies
MyBioSource
3 antibodies
Abbexa
6 antibodies
Creative Diagnostics
2 antibodies
MilliporeSigma / Merck KGaA
5 antibodies
Proteintech Group
1 antibody
Creative Biolabs
12 antibodies
Leading Biology
1 antibody
GenWay
3 antibodies
RayBiotech, Inc.
1 antibody